The extracellular environment possesses a rich milieu of biophysical and biochemical signaling cues that are simultaneously integrated by cells and influence cellular phenotype. Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (WWTR1; TAZ), two important signaling molecules of the Hippo pathway, have been recently implicated as nuclear relays of cytoskeletal ...

Maps of fire frequency, severity, size, and pattern are useful for strategically planning fire and natural resource management, assessing risk and ecological conditions, illustrating change in disturbance regimes through time, identifying knowledge gaps, and learning how climate, topography, vegetation, and land use influence fire regimes. We review and compare alternative data sources and appr...

An increase of urban flood risks is expected for the following decades not only because climate is becoming more extreme, but also because population and asset densities in cities are increasing. There is a need for models that can explain the damage process of urban flooding and support damage prevention. Recent improvements in flood modeling have highlighted the importance of urban topography...

The cerebellar role in non-motor functions is supported by the clinical finding that lesions confined to cerebellum produce the cerebellar cognitive affective syndrome. Nevertheless, there is no consensus regarding the overall cerebellar contribution to cognition. Among other reasons, this deficiency might be attributed to the small sample sizes and narrow breadths of existing studies on lesion...

The Iberian viticultural regions are convened according to the Denomination of Origin (DO) and present different climates, soils, topography and management practices. All these elements influence the vegetative growth of different varieties throughout the peninsula, and are tied to grape quality and wine type. In the current study, an integrated analysis of climate, soil, topography and vegetat...

This paper considers synthetic aperture radar (SAR) and other synthetic aperture imaging systems in which a backscattered wave is measured from positions along an arbitrary (known) flight path. The received backscattered signals are used to produce an image of the terrain. We assume a single-scattering model for the radar data, and we assume that the ground topography is known but not necessari...

Background: Three groups of factors related to topography, geology and hydrology have influence on the triggering of shallow landslides in soil material. In this paper a single representative factor (T-factor) for the topography is proposed, which can be used to define threshold values for the possibility of shallow soil slides. This study was carried out in the Dayi area, Guizhou Province, Chi...

The objective of this analysis was to identify topographic and bioclimatic factors that predict occurrence of forest and grassland patches within tropical montane forest-grassland mosaics. We further investigated whether interactions between topography and bioclimate are important in determining vegetation pattern, and assessed the role of spatial scale in determining the relative importance of...

Abstract When testing the surface quality of finest structures, white‐light interferometers are in their element, both production and development, as well laboratories research. This measurement principle works on almost all materials, operates without contact, providing profiles 3D with height resolutions nanometer range. Today, large‐area measurements just possible detailed investigations hig...