BACKGROUND The purpose of this study was to determine prospectively both human papillomavirus (HPV) load and physical status in different types of head and neck squamous cell carcinoma (HNSCC). METHODS HPV DNA, E6/E7 mRNA expression, viral load, and physical status of 184 patients with HNSCC were examined simultaneously by polymerase chain reaction (PCR)-based methods. RESULTS The HPV genom...

COMMUNICATIONSTO THE EDITOR 901 dosis to activity and generalization of the disease seems distinct. Positive tonsillar specimens were fewer than had been reported, but even lower figures have been quoted. These differences might be due to differences in selecting patients, and taking and processing biopsies. In tonsillar specimens, granulomas were sparsely located. Therefore, in some of our cas...

Gonorrhoea of the oral cavity has been demonstrated with increasing frequency in recent years among heterosexuals as well as homosexuals (Schmidt, Hjorting-flansen, and Philipsen, 1961; Cowan, 1969; Bro-Jorgensen and Jensen, 1971; Hellgren, 1971; Owen and Hill, 1972; Ratnatunga, 1972; Rodin, Monteiro and Scrimgeour, 1972; Odegaard and Gundersen, 1973; Wiesner, Tronca, Bonin, Pedersen, and Holme...

Tonsillar cancer incidence has been increasing in Sweden and many other western countries in the last decades despite that other head and neck cancers are decreasing. It is now established that Human Papillomavirus (HPV) can be accredited part of that increase. The aims of this thesis were to investigate any change in incidence of base of tongue cancer, any further increase of tonsillar cancer ...

OBJECTIVE We report a series of patients treated for carcinoma of the tonsil who either presented with bilateral carcinomas or later developed a second primary carcinoma of the contralateral tonsil. This report raises awareness of this occurrence. STUDY DESIGN Case series. METHODS Four cases have been identified of either concomitant or subsequent carcinoma of the contralateral tonsil inpat...

BACKGROUND The exact assessment of a tonsil carcinoma's size is often difficult because of the tumour's submucosal extension and deep infiltration. AIM The aim of the study is to assess the usefulness of intraoperative ultrasonography in tonsil cancer. MATERIAL Twenty patients with carcinoma of the tonsil were included in the study (squamous cell carcinoma keratosis - 12, squamous cell carc...

BACKGROUND The purpose of this study was to determine the rate of contralateral neck recurrence after surgery and unilateral neck radiotherapy, for lateralized tonsillar cancers with ipsilateral neck disease, in order to inform future clinical trial protocols for this disease. METHODS Patients with lateralized tonsillar squamous carcinoma (T1-T2, N0-N2b), treated with surgery and unilateral a...

BACKGROUND Paraneoplastic syndromes are systemic or organ-related functional tumor-associated changes that arise distant to the tumor. METHODS AND RESULTS We present a rare case of a 63-year-old man with dermatomyositis as a paraneoplastic syndrome developing more than a year before clinical manifestations of tonsillar squamous cell carcinoma (SCC). He subsequently developed stage T1N2bM0 IVA...