Motile activities such as chemotaxis and phagocytosis, which occur in Dictyostelium cells lacking myosin II, may be dependent upon myosin I. To begin to explore this possibility, we have engineered a disruption of the Dictyostelium myosin I heavy chain (DMIHC) gene described recently (Jung, G., C. L. Saxe III, A. R. Kimmel, and J. A. Hammer III. 1989. Proc. Natl. Acad. Sci. USA. 86:6186-6190). ...

NTRODUCTION FOR most of us living in the second half of the twentieth century, Herod the Great remains a shadowy figure who is recalled only at Christmas when we read of his massacre of the innocents (Matt. 2:16). He is even confused with Herod Agrippa who persecuted the Church and also died a miserable death (Acts 12:23). Our ancestors, however, were better informed since they often kept, on t...