نتایج جستجو برای: tissue harmonic imaging

تعداد نتایج: 1349927  

Journal: :Journal of synchrotron radiation 2012
R P Carnibella A Fouras M J Kitchen

Projection radiography of the chest has long been plagued by the presence of bony anatomy obscuring visibility of the lungs and heart. Dual-energy subtraction is a well known method for differentiating bone and soft tissue, but existing techniques are not ideally suited to dynamic imaging. Herein a new technique to address this problem is presented. The harmonic content of a monochromated X-ray...

Journal: :Biophysical journal 2005
Rebecca M Williams Warren R Zipfel Watt W Webb

Fibrillar collagen, being highly noncentrosymmetric, possesses a tremendous nonlinear susceptibility. As a result, second-harmonic generation (SHG) microscopy of collagen produces extremely bright and robust signals, providing an invaluable tool for imaging tissue structure with submicron resolution. Here we discuss fundamental principles governing SHG phase matching with the tightly focusing o...

2014
K. Heath Martin Brooks D. Lindsey Jianguo Ma Mike Lee Sibo Li F. Stuart Foster Xiaoning Jiang Paul A. Dayton

For many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics. Development of microbubble contrast agents over the past several decades has enabled ultrasound to distinguish between blood flow and surrounding tissue. Current clinical practices using microbubble contrast agents rely heavily on user training...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2011
Stefan Witte Adrian Negrean Johannes C Lodder Christiaan P J de Kock Guilherme Testa Silva Huibert D Mansvelder Marie Louise Groot

The ability to visualize neurons inside living brain tissue is a fundamental requirement in neuroscience and neurosurgery. Especially the development of a noninvasive probe of brain morphology with micrometer-scale resolution is highly desirable, as it would provide a noninvasive approach to optical biopsies in diagnostic medicine. Two-photon laser-scanning microscopy (2PLSM) is a powerful tool...

2010
Jo-Ya Tseng Ara A. Ghazaryan Wen Lo Yang-Fang Chen Vladimir Hovhannisyan Shean-Jen Chen Hsin-Yuan Tan Chen-Yuan Dong

Tissue glycation from diabetes and aging can result in complications such as renal failure, blindness, nerve damage and vascular diseases. In this work, we applied multiphoton microscopy for imaging and characterizing the extent of tissue glycation. The characteristic features of multiphoton autofluorescence (MPAF) and second harmonic generation (SHG) images as well as MPAF spectra of glycated ...

Journal: :The journal of physical chemistry letters 2013
Pu Wang Justin R Rajian Ji-Xin Cheng

The quantized vibration of chemical bonds provides a way of imaging target molecules in a complex tissue environment. Photoacoustic detection of harmonic vibrational transitions provides an approach to visualize tissue content beyond the ballistic photon regime. This method involves pulsed laser excitation of overtone transitions in target molecules inside a tissue. Fast relaxation of the vibra...

Journal: :Journal of biomedical optics 2005
Lily H Laiho Serge Pelet Thomas M Hancewicz Peter D Kaplan Peter T C So

Spectral resolved tissue imaging has a broad range of biomedical applications such as the minimally invasive diagnosis of diseases and the study of wound healing and tissue engineering processes. Two-photon microscopy imaging of endogenous fluorescence has been shown to be a powerful method for the quantification of tissue structure and biochemistry. While two-photon excited autofluorescence is...

Journal: :Ultrasonic imaging 2006
Caroline Maleke Mathieu Pernot Elisa E Konofagou

The harmonic motion imaging (HMI) technique for simultaneous monitoring and generation of ultrasound therapy using two separate focused ultrasound transducer elements was previously demonstrated. In this study, a new HMI technique is described that images tissue displacement induced by a harmonic radiation force using a single focused-ultrasound element. A wave propagation simulation model firs...

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