the incidence of traumatic brain injury (tbi) are annually increasing, developed tissue engineering methods could represent the definite remedies for patients with strongly injured central nervous system and have a great effect in the public healthcare cost. the current clinical treatments in tbi display several limitations. furthermore, several therapies, coming from neural tissue engineering ...

objective: different surgical procedures have been proposed for the treatment of gingival recessions. the goal of this study was to compare the clinical results of gingival recession treatment using subepithelial connective tissue graft and an acellular dermal matrix allograft. materials and methods: the present study was performed on 5 patients with 9 bilateral miller`s class i or ii gingival ...

background: the aim of this study was to fabricate the poly caprolactone (pcl) aligned nanofiber scaffold and to evaluate the survival, adhesion, proliferation, and differentiation of rat hair follicle stem cells (hfsc) in the graft material using electrospun pcl nanofiber scaffold for tissue engineering applications. methods: the bulge region of rat whisker was isolated and cultured in dmem: n...

background: infections include soft tissue infections are notable reason for hospital admission among idus, owing to unsterile injection techniques and equipment, contamination of drugs with organisms, and poor hygiene. in present case report a patient with profound limb infection is introduced. case: a 32 years old man was transferred to the emergency department. he was idu with iranian for 3 ...

background: wound healing of burned skin remains a major goal in public health. previous reports showed that the bone marrow stem cells were potent in keratinization and vascularization of full thickness skin wounds. methods: in this study, mesenchymal stem cells were derived from rat adipose tissues and characterized by flowcytometry. staining methods were used to evaluate their differentiatio...

brain injury is a complex event leading to tissue damage and functional deficits by primary and secondary mechanisms. since the application of tissue engineering approaches is a new topic in the treatment of brain injury, producing a proper experimental model to evaluate the effects of tissue engineering products on damaged brain tissue is required. in the present study, a simple and reproducib...

there are two main methods for preparing the puramatrix (pm) as a three-dimensional (3-d) scaffold for supporting the cells including surface plating and encapsulation. in the surface-plating procedure, the scaffold is created by adding an ionic agent such as medium to pm. after adjusting the ph by changing the medium, cells are seeded on top of the scaffold. in the encapsulation method, pm and...

background: the objective of the present study was to survey the presence of sarcocystis in sheep's brain in north khorasan province. methods: in general, 80 samples of sheep's brain were collected from slaugh-tered sheep in slaughterhouses of north khorasan province. tissue digestion method was used for observing bradyzoites in tissues. histopathological pro-cessing tracing sarcocystis and ens...

background: micropatterning is becoming a powerful tool for studying cells in vitro. this method not only uses very small amount of material but also mimic the microenvironment structure present in living tissues better than flask culturing techniques. in previous studies using micropatterning of extracellular matrix proteins on glass surfaces, the rate of protein detachment from the surface wa...

background: since the treatments of long tracheal leisions are associated with some limitations, tissue enginered trachea is considered as an alternative option. this study aimed at preparing a composite scaffold, based on natural and synthetic materials for tracheal tissue engineering. methods: nine chitosan silk-based scaffolds were fabricated using three freezing rates (0.5, 1, and 2°c/min) ...