Titanium (Ti) implants with long-term antibacterial ability and good biocompatibility are highly desirable materials that can be used to prevent implant-associated infections. In this study, titania nanotubes (TNTs) were synthesized on Ti surfaces through electrochemical anodization. Octenidine dihydrochloride (OCT)/poly(lactic-co-glycolic acid) (PLGA) was infiltrated into TNTs using a simple s...

Implant repair is a common means to restore the normal function of hard tissues (bone or teeth). At present, commonly and potentially used implant materials include titanium alloy (Ti), zirconia (Zr), polyetheretherketone (PEEK), 30% carbon fiber reinforced PEEK (CFR-PEEK). This study compares their physicochemical biological properties, including surface morphology, contact angle, nano hardnes...

The study monitored in vitro early response of connective tissue cells and immunocompetent cells to enosseal implant materials coated by different blood components (serum, activated plasma, and plasma/platelets) to evaluate human osteoblast proliferation and synthetic activity and inflammatory response presented as a cytokine profile of peripheral blood mononuclear cells (PBMCs) under condition...

PURPOSE The purpose of this study was to analyze the effects of two different implant surface treatments on initial bone connection by comparing the Removal Torque Values (RTQs) at 7 and 10 days after chemically modified, sandblasted, large-grit and acid-etched (modSLA), and Laser-etched (LE) Ti implant placements. MATERIALS AND METHODS Twenty modSLA and 20 LE implants were installed on the l...

OBJECTIVES To evaluate the reliability and failure modes of regular and horizontal mismatched platforms for implant-abutment connection varying the implant diameter. MATERIAL AND METHODS Regular (REG, n = 21, 4.0-mm-diameter implant) and horizontal mismatched (HM, n = 21, 4.6-mm-diameter implant) platform Ti-6Al-4V implants were restored with proprietary identical Ti-6Al-4V abutments and meta...

STUDY DESIGN Antimicrobial effect of a novel silver-impregnated pedicle screw in rabbits. OBJECTIVE A novel spine implant model was designed to study the antimicrobial effect of a modified Titanium (Ti) pedicle screws with methicillin-resistant Staphylococcus aureus (MRSA) in multiple surgical sites in the lumbar spine of a rabbit. SUMMARY OF BACKGROUND DATA Infection in spinal implant is o...

The application of implants for dental and orthopedic surgery has increased rapidly within the past few decades. In craniomaxillofacial surgery, different implant systems have been applied, for example, for dental and bone replacement or osteosynthesis plates and screws. These implants may be made of pure titanium or a titanium alloy, usually titanium-aluminumvanadium (Ti-6Al-4V). The surface c...

Previous studies have demonstrated that the modification of the titanium (Ti) surface of an implant with RGD (Arg‑Gly‑Asp) promotes the activity of osteoblasts. A novel Ti‑binding peptide, minTBP‑1, and a chimeric peptide, minTBP‑1‑PRGDN, have been synthesized to assist the fixing of RGD to Ti. In our previous study, minTBP‑1‑PRGDN demonstrated favorable affinity for Ti surfaces and facilitated...

Ti-based alloys are finding ever-increasing applications in biomaterials due to their excellent mechanical, physical and biological performance. Nowdays, low modulus β-type Ti-based alloys are still being developed. Meanwhile, porous Ti-based alloys are being developed as an alternative orthopedic implant material, as they can provide good biological fixation through bone tissue ingrowth into t...

Ti–6Al–4V foams are produced by the expansion of pressurized argon pores trapped in billets created by powder metallurgy. Pore expansion during thermal cycling (840–1030 C, which induces transformation superplasticity in Ti–6Al–4V) improves both the foaming rate (by reducing the flow stress) and the final porosity (by delaying fracture of the pores and subsequent escape of the gas), as compared...