Thyroglossal cysts are the most frequent neck malformation in children. They are usually located in the anterior midline near the hyoid bone, and may appear at the lingual (2.1%) or suprasternal (12.9%) level. Their presentation as a solitary thyroid nodule (STN) has been described in the literature and poses a challenge in the differential diagnosis of thyroid disorders in children. We present...

Thyroid surgeons are becoming increasingly more aware of a histologically distinct subset of thyroid carcinoma whose classification falls between well-differentiated and anaplastic carcinomas with respect to both cell differentiation and clinical behavior. This subtype of tumors has been categorized as poorly differentiated or insular carcinoma, based on its characteristic cell groupings. Altho...

Mucoepidermoid carcinoma of the trachea is a rare tumor. We report an 80-year-old male with mucoepidermoid carcinoma in the upper trachea with invasion of the isthmus of thyroid gland. The patient’s major symptom was dyspnea with coughing. Computed tomography scan showed a protruding mass into the trachea suspected of thyroid cancer. Ultrasonography also revealed the suspicion of an invasive th...

Here, we present the case of a patient with bilateral choroidal metastases with extraocular extension in one eye. Metastasis of papillary thyroid carcinoma to the uvea is extremely rare, with only 6 patients reported in the literature. A 62-year-old man with a prior history of papillary thyroid carcinoma suffered the rapid loss of vision in his right eye. He had neovascular glaucoma, total reti...

Background: Fine needle aspiration cytology can provide a reliable diagnosis in thyroid swellings and has become an investigation of choice due to its simplicity, specificity, accuracy, safety and cost-effectiveness. The objective of the study was to determine the reliability of FNAC in detecting various benign and malignant lesions of thyroid and correlate the results with histopathology, wher...

BACKGROUND Merkel cell carcinoma (MCC) is an uncommon neuroendocrine cutaneous carcinoma. Metastases to the thyroid gland are rare and may present diagnostic difficulties. CASE PRESENTATION A 73-year-old woman presented with a hard mass in the adipose tissue of the right inguinal area. This mass was surgically excised and the histology examination showed the existence of a MCC. CT scans revea...

Thyroid-like follicular carcinoma of the kidney (TLFCK) is an extremely rare subtype of renal cell carcinoma with close resemblance to the well-differentiated thyroid follicular neoplasms. TLFCK has not been included in the 2004 World Health Organization (WHO) classification due to the limited data available. Only 27 cases have been reported in the literature to date. Herein, we report a unique...

Purpose: The purpose of the present study was to investigate the effects of thyroid gland pathology on macro and trace elements of teeth. Methods: We examined two groups of patients: healthy patients and patients with thyroid disorders. The sample was comprised of 32 extracted teeth for orthodontic and periodontal indications from patients 18 to 50 years old. The changes in macro and micro trac...

An 80-year-old female presented with an incidental finding of a retrosternal mass on magnetic resonance imaging. Ultrasound demonstrated a mediastinal lesion adjacent to but separate from the inferior pole of the right thyroid lobe. Fine needle aspiration cytology demonstrated colloid and follicular cells. At surgery, the right thyroid lobe was found to be normal. A discrete 5 cm nodule was fou...

OBJECTIVES/HYPOTHESIS To define molecular biology in clinical practice for diagnosis, surgical management, and prognostication of differentiated thyroid cancer. DATA SOURCES Ovid Medline 2006-2012 REVIEW METHODS Manuscripts with clinical correlates. RESULTS Papillary thyroid carcinomas harbor point mutations of the BRAF and RAS genes or RET/PTC rearrangements, all of which activate the mi...