Subclinical hypothyroidism (SCH) has been associated with increased cardiovascular mortality due to adverse effects mainly on lipids and blood pressure (BP). There is evidence that SCH, especially in patients with thyroid-stimulating hormone (TSH) >10mU/l, may increase cardiovascular risk. Some uncertainty exists regarding the association of SCH with BP; however, that the coexistence of SCH wit...

Patients with thyroid disease are seen in many diVerent general and specialist clinics because of the many and varied modes of presentation. This review will highlight recent developments in aspects of pathophysiology and clinical management of thyroid disorders but will inevitably not be all inclusive. Recent developments in molecular biology have had important eVects on our understanding of m...

Thyroid disorders and diabetes mellitus are two of the most common endocrine conditions, which occur with greater frequency along with each other. This communication describes current knowledge about these twin diseases. Epidemiology, clinical features, laboratory abnormalities, screening and therapeutic implication of this relationship are discussed. The article underlines the clinical relevan...

Nitric oxide has been regarded as a marker of oxidative stress in various diseases. There is a lot of controversy regarding levels of nitric oxide in thyroid disorders. The present study included 50 diagnosed hypothyroid, 50 hyperthyroid and 50 healthy controls. The nitric oxide levels were estimated by Griess reaction. The results were compared statistically. Nitric oxide concentration was fou...

Background: In Nigeria, and perhaps other African countries, thyroid disorders in childhood and adolescence have not been sufficiently studied. Where studies are available, they were either conducted decades ago or they involved only adults. Objective: To describe the pattern of thyroid disorders among children and adolescents seen in a Nigerian teaching hospital and highlight the management ch...