This research identified psychosocial factors associated with post-traumatic stress and health anxiety following a venous thrombotic embolism. In all, 158 participants, largely registered with a venous thrombotic embolism information website (Lifeblood: The Thrombosis Charity), completed an online survey. Post-traumatic symptom scores were linked to health threat, and not moderated by perceived...

Data available in the United Kingdom through the Medical Research Council's General Practice Research Framework were recorded in a study of 603 women aged 45-69 with confirmed diagnoses of stroke or myocardial infarction, each matched by age with two controls. Current cigarette smoking and a family history of myocardial infarction were both strongly associated with the risk of stroke and myocar...

Two brothers and one sister had three variants of thrombotic thrombocytopenic purpura and haemolytic uraemic syndrome (the 'TTP-HUS' complex). The sister had a chronic fatal variant of thrombotic thrombocytopenic purpura with severe neurological manifestation. One brother had a chronic relapsing disease but the kidneys were not affected, and the other brother had haemolytic uraemic syndrome. Th...

Although early occlusion of saphenous vein coronary artery bypass grafts is usually thrombotic, late occlusion is most often a result of progressive intimal fibromuscular proliferation or atheroma formation in the implanted vein. We describe another mechanism of late graft occlusion: atheromatous plaque rupture with superimposed occlusive thrombosis. Four men, ages 48-67 years underwent repeat ...

Although early occlusion of saphenous vein coronary artery bypass grafts is usually thrombotic, late occlusion is most often a result of progressive intimal fibromuscular proliferation or atheroma formation in the implanted vein. We describe another mechanism of late graft occlusion: atheromatous plaque rupture with superimposed occlusive thrombosis. Four men, ages 48-67 years underwent repeat ...

Multiple sclerosis (MS) and anti-phospholipid syndrome (APS) are chronic, immune-mediated, relapsing-remitting disorders affecting young adults. APS is characterized by thrombosis pregnancy mortality associated with antibodies. The diagnosis of may be difficult, it not uncommon for patients to misdiagnosed multiple sclerosis. In this case report, we describe a patient who was diagnosed as havin...

A recently described genetic variant of the prothrombin gene (G to A transition at nucleotide position 20210) is associated with an increased risk of venous thrombosis (1). The 20210A prothrombin allele may precipitate cerebral ischemia or myocardial infarction in young patients with known prothrombotic abnormalities (2, 3). Similarly, it has been demonstrated that factor V Leiden further incre...

For the first time on Fergana Valley model, prognostic markers of risk thrombotic complications in COVID-19 patients with type 2 diabetes were studied. It was found that level glycemia, concentration proinflammatory cytokines IL-6, ferritin and CRP, marker thrombus formation - d dimer, have a significance, maximum significance CRP. The ultrasound aspect thrombosis branches PA against background...

High quality, large prospective population-based studies are like well-tended orchards: they take many years to bear fruit, but when they do, they yield a bounty. In this issue of Arteriosclerosis, Thrombosis, and Vascular Biology, fruit is on offer from 2 important Danish population-based studies, the Copenhagen City Heart Study and the Copenhagen General Population Study, which previously pro...

We have developed an enzyme-linked immunosorbent immunoassay for quantifying the immediate precursor proteins to intravascular thrombi. This thrombus precursor protein (TpP) assay identifies active thrombosis in several clinical conditions, including early myocardial infarction (MI). In a study of patients recruited for the GUSTO intervention study, MI patients had concentrations of TpP 4-20-fo...