Aneurysms of the major thoracic veins are rare. They are usually asymptomatic and thus treated conservatively. We report an extremely rare case of rapidly progressing superior vena cava (SVC) aneurysm complicated by thrombosis and acute pulmonary thromboembolism (PTE) with right ventricular dysfunction. Thrombolytic therapy for hemodynamically significant acute PTE was harmful to the patient in...

The management of patients with venous thromboembolism (VTE) is a common clinical scenario that, for the most part, involves well‑established, evidence‑based treatment pathways. However, important unanswered clinical questions remain that are the focus of ongoing research. The aim of this narrative review is to provide a practical, case‑based approach to the following clinical scenarios in whic...

Cardiovascular disease (CVD) is among the leading causes of death in world caused by thrombosis. Thrombosis formation excessive blood clots on walls vessels called thrombus. This could lead to fatal blockage heart muscle or brain. can be treated using enzyme-type drugs such as thrombolytic proteases. There have been many studies bacteria producing enzymes isolated from fermented foodstuffs. How...

Dural venous sinus thrombosis (DVST) in the neonatal period has a spectrum of clinical and radiologic findings. At the present time, the treatment for venous sinus thrombosis is mainly one of supportive therapy. In a patient with documented DVST, whose clinical status is deteriorating despite conventional supportive therapy, there may be a rationale for more aggressive therapy. We report a case...

The use of thrombolytic agents to rapidly lyse the clot has emerged as a therapeutic modality, in concert with interventional neuroradiologic approaches to deliver the agent locally at the site of thrombosis.There are no randomized, double blind, placebo, controlled trials to support thrombolysis as a first line therapy in patients with cerebral venous sinus thrombosis compared to standard ther...