نتایج جستجو برای: thr

تعداد نتایج: 7085  

Journal: :Chemical communications 2012
Si Jia Pan Jakub Rajniak Mikhail O Maksimov A James Link

The conserved threonine (Thr) residue in the penultimate position of the leader peptide of lasso peptides microcin J25 and capistruin can be effectively replaced by several amino acids close in size and shape to Thr. These findings suggest a model for lasso peptide biosynthesis in which the Thr sidechain is a recognition element for the lasso peptide maturation machinery.

Journal: :Molecular pharmacology 2000
T M Palmer G L Stiles

Activation of the A(3) adenosine receptor (A(3)AR) contributes to the cardioprotective, bronchoconstrictive, and hypotensive effects of adenosine. Agonist occupation of the A(3)AR results in a rapid desensitization of receptor function, which is associated with the phosphorylation of the receptor protein by one or more members of the G protein-coupled receptor kinase family of protein kinases. ...

Journal: :Frontiers in cell and developmental biology 2016
Tara M. Formisano Lon J. Van Winkle

Stem cells are at the forefront of current regenerative and biomedical research. Thus, there exists an imperative and urgent need to understand the mechanisms that drive stem cell function in order to exploit their use as a therapeutic tool. Amino acids are potent inducers of signaling cascades that drive stem cell proliferation and differentiation. With a focus on mouse embryonic stem (mES) ce...

2012
Sharon L Brennan Tyman Stanford Anita E Wluka Margaret J Henry Richard S Page Stephen E Graves Mark A Kotowicz Geoffrey C Nicholson Julie A Pasco

BACKGROUND The utilization of total hip replacement (THR) surgery is rapidly increasing, however few data examine whether these procedures are associated with socioeconomic status (SES) within Australia. This study examined primary THR across SES for both genders for the Barwon Statistical Division (BSD) of Victoria, Australia. METHODS Using the Australian Orthopaedic Association National Joi...

Journal: :PLoS ONE 2008
Stefan Amisten Oscar Ö. Braun Lovisa Johansson Martin Ridderstråle Olle Melander David Erlinge

BACKGROUND AND AIMS The aims of this study were to investigate (1) if P2Y(12) polymorphisms defining the P2Y(12) H2 allele are associated with any other SNPs that may explain the previously reported association with increased ADP induced platelet activation and association with peripheral arterial disease and coronary artery disease and (2) if such variants are associated with acute myocardial ...

Journal: :The Journal of biological chemistry 1986
K Kitajima Y Inoue S Inoue

Polysialoglycoproteins (PSGP) we first isolated from the unfertilized eggs of rainbow trout (Salmo gairderi) and now found to be a ubiquitous component of Salmonidae fish eggs are a novel type of glycoprotein. PSGP from rainbow trout has a molecular weight of 200 X 10(3), a low protein content (about 15% w/w), and a high sialic acid (N-glycolylneuraminic acid (NeuGc] content (about 60%, w/w). I...

2015
Yue Hu Zhenggang Li Cheng Yuan Xuejiao Jin Lijie Yan Xiaofei Zhao Yongliang Zhang Andrew O. Jackson Xianbing Wang Chenggui Han Jialin Yu Dawei Li

The barley stripe mosaic virus (BSMV) triple gene block 1 (TGB1) protein is required for virus cell-to-cell movement. However, little information is available about how these activities are regulated by post-translational modifications. In this study, we showed that the BSMV Xinjiang strain TGB1 (XJTGB1) is phosphorylated in vivo and in vitro by protein kinase CK2 from barley and Nicotiana bent...

2014
Rotem Meiri Talli Y Rosenbaum Leonid Kalichman

BACKGROUND More than 1 million total hip replacements (THRs) are performed every year worldwide. Achieving decreased pain, increased mobility, and improved quality of life (QoL) are key factors in the decision to undergo THR. Sexual activity is a valued component of QoL; however, little is known about how THR affects sexual functioning or the extent to which health care providers address sexual...

Journal: :Poultry science 2015
W Siegert H Ahmadi A Helmbrecht M Rodehutscord

Differences in the optimal dietary concentrations of Gly (glycine) and Ser (serine) in broiler diets may be due to levels of endogenous Gly precursors that differ in literature. Therefore, we measured the extent of the interactive effects between equivalents of Gly and Ser (Glyequi) and the endogenous Gly precursors choline and Thr (threonine) on growth performance. A fractional central composi...

2012
Jasvinder A Singh David G Lewallen

BACKGROUND AND PURPOSE There have been no published studies assessing the possible association of medical comorbidities with periprosthetic fracture risk. We therefore assessed whether medical comorbidity is associated with risk of periprosthetic fractures after total hip replacement (THR). MATERIAL AND METHODS We used prospectively collected data from 1989-2008 in the Mayo Clinic Total Joint...

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