conclusions this study shows that an adequate nutritional support, in patients with severe burn injury, can improve sofa score. it is also more cost-effective, resulting in a shorter los in hospital. background severe burned patients developed metabolic imbalances and systemic inflammatory response syndrome (sirs), which can lead to malnutrition, impaired immunologic response, multiple organ fa...

BACKGROUND Infection is a common cause of morbidity and mortality in burn patients. Clinical diagnosis of bacteremia and/or sepsis in burn patients is difficult for a number of reasons. It could be symptomatic and/or asymptomatic as a result of immune deficiency secondary to thermal injury. METHODS A cross sectional study was conducted at Yekatit 12 Hospital Burn Center. Blood specimen and wo...

OBJECTIVE Nerium oleander (Apocynaceae) and Aloe vera (Liliaceae) are among the widely used herbal remedies for treating skin diseases and possess numerous activities such as antibacterial, antiviral, antifungal, and antioxidant. The aim of this study was to investigate the possible wound healing effect of Aloev era-based extract of the N. oleander leaf (NAE-8®) based on its antioxidant, anti-i...

Tropoelastin (TE), the soluble precursor of insoluble elastin fibers, is produced in minimal amounts in adults. Burn injuries result in inflexible collagen-rich scars because of lack of elastin fiber formation. We studied the feasibility of using recombinant human tropoelastin to enable elastin fiber production in burn and surgical scars to improve skin flexibility. In a swine hypertrophic burn...

A significant proportion of the mortality and morbidity of severe burns is attributable to the ensuing hypermetabolic response. This response can last for as long as 1 year after injury and is associated with impaired wound healing, increased infection risks, erosion of lean body mass, hampered rehabilitation, and delayed reintegration of burn survivors into society. Pharmacologic and nonpharma...

BACKGROUND Pulmonary failure has emerged as one of the leading causes of mortality in burned children due, in part, to the success in reducing the incidence of sepsis, early surgery and fluid resuscitation, and new advances in nutritional support. To evaluate the effect of pulmonary injury, age, gender, race, and burn size on mortality, the records of 3179 burned children admitted to our burn c...

This study was undertaken to assess the parameters that may predict maternal and foetal outcome in 49 thermally injured pregnant women in a Plastic surgery unit in tertiary referral center in the last five years. There were 33 maternal deaths and 34 fetal deaths. In general, pregnancy as such does not influence maternal outcome after thermal injury. In first and second trimester best chance for...

Background: Thermal wounds are relatively uncommon in veterinary practice and most of them are the result of accidental burns. Patients with severe burns are among the most challenging cases presented to veterinarians, because severe burn injury leads to significant hemodynamic instability, massive fluid shifts, and hypovolemia requiring prompt and aggressive therapy. Because severe burn injury...

Two new techniques for investigating the thermal skinburn potential of airbags are presented. A reduced-volume airbag test procedure has been developed to obtain airbag pressures that are representative of a dynamic ridedown event during a static deployment. Temperature and heat flux measurements made with this procedure can be used to predict airbag thermal burn potential. Measurements from th...