We tested the contribution of two mechanisms, response expectancy and motivational concordance, to reported psychological benefit from a popular, biologically inactive, self-help, complementary therapy (a placebo). Flower essences were taken by 251 people for self-selected symptoms and were randomized to receive three different kinds of information. When the flower essence was presented as a sp...

Higher plants have long been used as traditional medicines to treat human ailments. Approximately 80% of people worldwide utilize safe sources heal diseases via a totally new medicinal system. Holigarna ferruginea is an indigenous tree plant in the Anacardiaceae family. The has wide range physiologically active chemicals. GC-MS was screen phytochemical substances, while FTIR identify functional...

obesity with an increasing prevalence rate worldwide is correlated with multiple comorbidities. unfortunately, the currently available therapies such as the pharmacotherapy, bariatric surgery or gene-transfer technology are associated with a number of disadvantages including undesirable side effects, poor compliance or transient effectiveness. therefore, modifications of the lifestyle factors m...

sirolimus is a potent immunosuppressive agent administered as prophylactic agent to prevent rejection after organ transplantation. sirolimus must be used within a narrow therapeutic window. due to inter- and intra-variability, sirolimus blood concentrations may be affected, therefore, there is no possibility of predicting the sirolimus blood concentrations based on the dose patients received. t...

The aim of the study was to produce a model form of a drug of anti-inflammatory activity designed for application in oral cavity. An attempt was made to choose hydrogel vehicle which would ensure not only high pharmaceutical availability of the therapeutic agent but appropriate theological properties of the drug as well. Variant prescriptions with ketoprofen were worked out which differed in th...

fecal microbiota transplant (fmt) research trials are growing in diverse intestinal and extraintestinal conditions that are thought to be either caused or correlated with gut microbiota dysbiosis. although, the mechanism by which the microbiota results in disease initiation or progression is not fully understood, it is speculated that restoring the symbiosis by fmt could have therapeutic benefits.

conclusion superselective tae for lgi bleeding has a high success and low complication rate. there are no statistical correlations between the clinical success rate and several variables, including embolic material, embolization site, and anticoagulant or antiplatelet medication. patients and methods fifty-two patients who underwent superselective tae for lgi bleeding between 2003 and 2011 were...

discussion splenic artery aneurysm is a very uncommon cause of page kidney and to our knowledge, it was the first case of its kind ever reported in the literature. introduction the page kidney is a rare phenomenon that refers to hypertension resulting from any external compression of a kidney by a hematoma, tumor, lymphocele, or urinoma. the activation of the renin-angiotensin-aldosterone syste...

The determination of single high doses of active pharmaceutical ingredients (API) is used mostly to fulfill regulatory demands. Oral LD(50) values in animals for over 300 API were compared to the minimal effective therapeutic doses (METD) in humans in order to find a correlation between animal and human data. The highest correlation between human METD and animal LD(50) was found for the dog (R=...