The survival, OER, and RBE for HeLa, leukemia, and kidney cells after irradiation with 14 MeV neutrons, pion beams, and heavy ion beams dispersed by ridge filters are calculated. Simple beam models and the delta-ray theory of cellular survival are used in the calculations, which refer to a mixed radiation environment and the potential application of these irradiation systems in radiotherapy.

Ion induced desorption is a severe luminosity limitation for low charge state heavy ion accelerators. Therefore, it was intensively investigated in dedicated experiments during recent years. Several experimental results were obtained providing numerous desorption yields for different ion beam parameters and different materials as well as surface treatments. The heavy ion induced desorption was ...

The average or amorphous track model uses the response of a system to gamma-rays and the radial distribution of dose about an ion's path to describe survival and other cellular endpoints from proton, heavy ion, and neutron irradiation. This model has been used for over 30 years to successfully fit many radiobiology data sets. We review several extensions of this approach that address objections...

Dehydration is the danger signal of infantile diarrhoea because without dehydration the mortality from properly treated gastro-enteritis should be negligible, hence the importance of preventing dehydration and the recognition that its presence indicates a medical emergency. Important constituents of both extracellular and intracellular body fluids are the electrolytes, and Gamble (1947) conside...

The field of nanobiotechnology mainly encompasses with physics, biology, chemistry and material sciences and it develops novel therapeutic nano-scale materials for biomedical, drug delivery, cancer therapy and pharmaceutical applications. Silver nanoparticles (AgNPs) have unique physiochemical, biological and environmental properties which make them useful in a wide range of applications, s...

We present a technique by which it is possible to produce a planar sensor for ion channel electrophysiology from glass substrates. Apertures with diameters in the low micrometer to submicrometer range are achieved by irradiation of a glass chip with a single heavy ion and subsequent wet track etching. The function of the device is demonstrated by recordings of single channel currents mediated b...

Nanostructuring of surfaces and two-dimensional materials using swift heavy ions offers some unique possibilities owing to the deposition of a large amount of energy localized within a nanoscale volume surrounding the ion trajectory. To fully exploit this feature, the morphology of nanostructures formed after ion impact has to be known in detail. In the present work the response of a rutile TiO...

In geological minerals, tracks of fragments from spontaneous fission of U nuclei accumulate over geological time scales and are widely used for fission-track dating and thermochronology [1, 2]. In our recent studies, we tackled the problem how solids exposed to energetic heavy ions cope with the simultaneous exposure of external pressure. This combination of ion irradiation and pressure is suit...

Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na+). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at human dopamine D2 and dopamine D3 receptor subtypes, which are important therapeutic targets for the treatment of psyc...

charge as an ion, and ot its appearing to be composed of positive and negative electricity and nothing else is dwelt on, and a feature is made of the therapeutic effects of the introduction of ions by electrolysis. The consideration of X-rays is much fuller than in the last edition, and this amplification is not confined to the chapter on the Rontgen Xrays, but consists also in considerable add...