UNLABELLED Information on the prognostic value of noninvasive stress imaging techniques in the elderly is relatively scarce. This study assessed the prognostic value of dobutamine stress (99m)Tc-tetrofosmin SPECT for the prediction of mortality and cardiac events in elderly patients. METHODS Clinical information and SPECT results were analyzed for 272 consecutive patients > or = 65 y old (mea...

UNLABELLED Stress myocardial perfusion imaging is a useful method for evaluation of coronary artery disease (CAD) in patients with diabetes mellitus. However, its role in predicting all-cause mortality is not well defined. The aim of this study was to determine whether myocardial ischemia on stress myocardial perfusion imaging can predict all causes of death in patients with diabetes mellitus. ...

A 73-year-old man with aortic regurgitation was examined by 123I-alpha-methyl-p-iodophenylpentadecanoic acid (BMIPP) myocardial single photon emission computed tomography (SPECT) in 1995. Myocardial accumulation was not evident on either the early or the delayed image obtained 15 minutes and 3 hours, respectively, after injecting 123I-BMIPP. Flow cytometric analysis of CD36 expression in monocy...

UNLABELLED A high number (30%-50%) of reversible defects have been detected early after coronary balloon angioplasty. Inadequate luminal enlargement despite a good angiographic appearance has been suggested as a possible mechanism of these perfusion abnormalities, and some reports have shown better coronary flow reserve after coronary stent implantation than after balloon dilatation. The primar...

UNLABELLED The radioactivity in the organs adjacent to the heart causes interference with the quantitative assessment of myocardial uptake of tracer on scintigraphy. In order to investigate how much the functions of these organs affect myocardial uptake seen in imaging, we compared the myocardial uptake measured by means of a gamma camera with the actual activity in the excised organs. METHOD...

UNLABELLED Cadmium zinc telluride (CZT) detectors with linear counting rate response enable count subtraction in sequential scanning. We evaluated whether count subtraction eliminated the need for higher activity doses in the second part of the 1-d stress-rest myocardial perfusion imaging (MPI) protocol. METHODS For 50 patients (mean age ± SD, 66 ± 12 y) with visually abnormal (n = 42) or equ...

Received 3/25/2005; revised 4/2/2005; accepted 4/8/2005. For correspondence or reprints contact: Wei-Jen Shih, M.D., Nuclear Medicine Service, 1101 Veterans Drive, VA Medical Center, Lexington KY, USA. Tel: (606) 381-5928, Fax: (606) 323-2171, E-mail: [email protected] During acquisition of Tc labeled perfusion agents or Tl-thallous chloride (Tl) gated cardiac SPECT the field area covered includes...

UNLABELLED The utility of (99m)Tc-tetrofosmin myocardial SPECT for assessment of pulmonary hypertension and right ventricular thickness has not been well studied. We hypothesized that a ratio of right ventricular activity to left ventricular activity (RV/LV uptake ratio) from SPECT myocardial perfusion images could identify the presence of increased right ventricular wall thickness and elevated...