we report two cases of tetralogy of fallot with pulmonary valve bacterial endocarditis where one extended to the branch of pulmonary artery (pa). this is a rare occurrence. aggressive supportive care plus early and radical surgery can be life saving.

a 22-year-old woman presented with acute left-sided pleuritic chest pain and dyspnea 6 days after surgery for revision of the stenotic central aortopulmonary shunt. she had a history of tetralogy of fallot (tof), pulmonary valve stenosis, ventricular septal defect and major aortopulmonary collateral artery. her waterston shunt was placed when she was 5 years old and stented and re-dilated after...

Background Tetralogy of Fallot is the most common cyanotic congenital heart disease. However, its pathogenesis remains to be clarified. The purpose of this study was to identify the genetic variants in Tetralogy of Fallot by whole exome sequencing. Methods Whole exome sequencing was performed among eight small families with Tetralogy of Fallot. Differential single nucleotide polymorphisms and...

Background Good quality of life correlates with a good exercise capacity in daily life in patients with Tetralogy of Fallot (TOF). Patients after correction of TOF usually develop residual defects as pulmonary regurgitation or pulmonary stenosis of different severity. We investigated the impact of several hemodynamic parameters measured by cardiovascular magnetic resonance (CMR) and echocardiog...

IN RECENT YEARS the morphological features of the major portions of the atrioventricular (A-V) conduction system of human hearts that were afflicted with various congenital anomalies have been described.1-6 These reports have contrasted the anatomy of the A-V conduction system in examples of ventricular septal defect (VSD) and tetralogy of Fallot with that configuration found in defects of the ...

BACKGROUND Public-health guidelines recommend patients with congenital heart disease to exercise. Studies have shown that patients with congenital heart disease can improve physical exercise capacity. The effect of training on regional ventricular performance has hardly been studied. We performed a pilot study to assess whether an exercise training program would result in adverse changes of reg...

The widespread application of echocardiography to the field of congenital heart disease has led to the development of a concept of "echocardiographic discontinuity" for the diagnosis of some conditions. Although this is a valuable sign in differentiating such entities as tetralogy of Fallot, truncus arteriosus and double outlet right ventricle, the reported cases illustrate that the echocardiog...

Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease. A 47-year-old woman presented to our clinic with cyanosis and dyspnea on exertion. She had previously had three successful and healthy pregnancies. From the results of laboratory and imaging techniques a diagnosis of tetralogy of Fallot was made and the patient was referred to the cardiovascular surgery for the repa...