BACKGROUND Cisplatin (CP) is widely used in clinic to treat the solid tumors. However, CP is associated with some major side effects including nephrotoxicity, hepatoxicity, and testicular toxicity. OBJECTIVES To found, which of the toxicities is the first side effect of CP. MATERIALS AND METHODS we conducted a pilot research on 12 adult male Wistar rats. RESULTS One week after CP administ...

Endocrine disputer chemicals (EDCs) such as 4-tert-octylphenol (OP), are a class of exogenous pollutants that can interfere with normal physiological processes, resulting in number health issues. Therefore, the goal current study is to determine how well α -lipoic acid (LA) protects against DNA damage brought on by OP. Forty male albino rats were randomly assigned into four groups. Group I (con...

Cobalt-60 Irradiation/Testis/House Sparrow (Passer domesticus, Linn.) Adult male house sparrows were exposed to Co-60 external irradiation at doses of 475, 712 and 950R. The dose rate was 100 R/hr at a distance of one foot. The birds were autopsied at intervals of 1, 3, 5, 7 and 15 days after irradiation. Testes were studied for histopathological damage produced. There was a significant loss of...

Undescended testis is one of the most common pediatric disorder of the male endocrine glands and the most common genital disorder identified at birth. The undescended testis may be palpable or non-palpable. Approximately 20% of undescended testis are non-palpable and either located in the abdomen or the canaliculi, or atrophic or are completely absent. Identifying the location of ectopic and un...

Background: Quantum dots (QDs) are among the most promising items in the nanomedicine toolbox. These nanocrystal fluorophores have several potential medical applications including nanodiagnostics, imaging, targeted drug delivery, Nevertheless, in vivo cytotoxicity of these nanoparticles has not been highly considered. For this reason, the cytotoxic effects of CdSe QDs on testis and epididymis e...

The Sertoli cell is a critical somatic that initiates the development of testicular morphology and determines important parameters for spermatogenic function. blood-testis barrier, also known as barrier one tightest tissue barriers in mammalian body, an immunological to separate post meiotic germ antigens from systemic circulation. Additionally, creating unique microenvironment spermatocytes ex...

The current study aimed to detect specific types of ADAM proteins in the bovine sperm. Histology tissue male reproduction was involved with testis, head, body, and tail epididymis. Results showed that testis composed parenchyma contained seminiferous tubules which are surrounded by two layers externally tunica vaginalis internally albuginea. PAS positive lumen, epithelium body epididymis, Where...