Attractin (Atrn), an autosomal recessive gene, is widely expressed in the body and displays multiple physiological and pathological functions in different types of tissues. The objective of this study was to localize Atrn protein and mRNA in the testis and epididymis of rats at different stages of maturation. Testis and epididymidis samples were obtained from the following 5 groups of Sprague D...

OBJECTIVE The transcription factors GATA-1 and GATA-4 have been implicated in the regulation of testicular development and function. Their cofactors FOG-1 and FOG-2 are expressed in the gonads, but their cell-specific and developmental expression in the testis remains unresolved. Therefore, we analyzed GATA-1, GATA-4, FOG-1 and FOG-2 expression in detail, from undifferentiated male urogenital r...

Males and females exhibit highly dimorphic phenotypes, particularly in their gonads, which is believed to be driven largely by differential gene expression. Typically, the protein sequences of genes upregulated in males, or male-biased genes, evolve rapidly as compared to female-biased and unbiased genes. To date, the specific study of gonad-biased genes remains uncommon in metazoans. Here, we ...

Despite the great advances in sequencing technologies, genomic and transcriptomic information for marine non-model species with ecological, evolutionary, and economical interest is still scarce. In this work we aimed to identify genes expressed during spermatogenesis in the functional hermaphrodite scallop Nodipecten subnodosus (Mollusca: Bivalvia: Pectinidae), with the purpose of obtaining a p...

XX male is a kind of sexual differentiation disorder that affects one out of every 20,000 to 25,000 male births. The patients have male phenotypes with female chromosomes, the karyotype 46XX. More than 150 XX males have been reported in the medical literature since Albert de la Chapelle first reported a male human with a pure XX sex chromosome constitution in 1964.1,2 Most patients with this co...

A brain aromatase gene was identified from the Nile tilapia Oreochromis niloticus. The cDNA sequence of this gene differed from that of the ovarian aromatase gene previously reported from this species. Tissue specific expression for both brain and ovarian aromatase genes was examined in the tissues of adult tilapia. Brain aromatase mRNA was expressed in the brain, kidney, eye, ovary, and testis...

objective(s):  medicinal benefits of quantum dots have been proved in recent years but there is little known about their toxicity especially in vivo toxicity. in order to use quantum dots in medical applications, studies ontheir in vivo toxicity is important.  materials and methods:cdse:zns quantum dots were injected in 10, 20, and 40 mg/kg doses to male mice10 days later, mice were sacrificed ...

Brain sexual differentiation is orchestrated by precise coordination of sex steroid hormones. In some species, programming of select male brain regions is dependent upon aromatization of testosterone to estrogen. In mammals, these hormones surge during the organizational and activational periods that occur during perinatal development and adulthood, respectively. In various fish and reptiles, i...

HULL, E. Effects o f neonatal exposure to progesterone on sexual behavior o f male and female rats. PHYSIOL. BEHAV. 26(3) 401--405, 1981 .--Lactating females received daffy injections of progesterone or off, and their offspring were gonadectomized in adulthood and tested for both musculine and feminine sexual behavior elicited by estrogen, progesterone, and testosterone regimens. Male offspring...