In a postmortem survey of children with leukaemia and lymphoma, the overall incidence of testicular infiltration was 65% and of ovarian infiltration 66%. In acute lymphoblastic leukaemia, testicular infiltration was found in 25 of 39 cases and ovarian infiltration in 6 of 12 cases. The majority of boys with acute lymphoblastic leukaemia and testicular infiltration also had infiltration in other...

objective: cryopreservation of immature testicular tissue should be considered as an important factor for fertility preservation in young boys with cancer. the objective of this study is to investigate whether immature testicular tissue of mice can be successfully cryopreserved using a simple vitrification procedure to maintain testicular cell viability, proliferation, and differentiation capac...

We report a very rare case of bilateral high origins of testicular arteries in a 66-year-old Chinese male cadaver. The arteries originated from the antero-lateral aspect of the abdominal aorta, cranially to the origins of ipsilateral renal arteries. Approximately 1.1 cm after its origin, the right testicular artery gave off the middle suprarenal artery. During its course, the artery crossed ant...

OBJECTIVE [corrected] To report a rare case of secondary testicular plasmocytoma in the context of a testicular mass. METHOD We introduced a patient with plasmocytoma and a testicular infiltration of his systemic affection. RESULT An inguinal orquiectomy was performed to treat the testicular infiltration and no recurrence of the process was seen after 6 months of follow up. CONCLUSIONS Pl...

BACKGROUND Clusterin, a heterodimeric glycoprotein of approximately 80 kDa, exists extensively in human body fluids. The abnormal expression of clusterin is closely related to the occurrence, progression, and prognosis of tumors. Up to now, few studies have focused on clusterin in human testicular cancer. This study describes an extensive exploration of the presence and expression of clusterin ...

Introduction. Testicular cancer and a multiple birth are both rare events, and the risk of testicular cancer is increased in twins. In Lithuania, only five quadruplets have been recorded since the middle of the 20th century. In this report, we present two rare events in one family: testicular cancer in two brothers of a quadruplet (three brothers and a sister). Case description. Both patients w...

Leukocytes, specifically macrophages, lymphocytes and mast cells, are found within the testes of most, if not all, mammals. In some species (for example, rats, mice and humans), the number of 'resident' testicular macrophages, in particular, is quite considerable. However, reproductive biologists are only beginning to explore the characteristics and possible biological significance of these cel...

BACKGROUND The risk of testicular cancer is thought to be higher among men seeking infertility treatment compared with the general population. Confirmation of this risk in a large US cohort of at-risk patients is lacking. This study explored the association between male infertility and subsequent development of testicular cancer in a US-based cohort. METHODS A total of 51 461 couples evaluate...

Recovery of testicular spermatozoa from azoospermic patients with testicular failure, followed by intracytoplasmic sperm injection (ICSI) is a recent advance in the treatment of male infertility. In most cases, free spermatozoa are recovered from testicular tissue after mechanical mincing of multiple biopsies. Testicular sperm retrieval, however, remains unsuccessful in 30-50% of male patients ...

AIM To review the causes and principles and recent concepts in the management of testicular pain. INTRODUCTION Chronic testicular pain is a common presenting symptom in genitourinary surgery. Due to increased awareness of testicular cancer and in men's health more cases are likely to be referred. MATERIAL AND METHODS A literature search was made for abstracts, original papers and review art...