Subsequent to the definitive studies of Craig,’ Pryor and Wyatt,2 and others, endomyocardial fibroelastosis has been recognized as a distinct pathological entity even though certain details are not yet fully clarified. Several recent papers2-6 have brought knowledge of its clinical aspects to the point where it is almost as well defined clinically as pathologically. At first glance, it might se...

In the 30 years since the founding of the American Academy of Psychiatry and the Law in 1969, there has been a tremendous growth in the organization as well as in the number of psychiatrists who have a subspecialty of forensic psychiatry. In an attempt to explain this exponential growth, the author looks at the many social, economic, medical, and legal activities that were active during these y...

The historical demonstration by Furchgott and Zawadzki that removal of the endothelium abrogates the in vitro vasodilator effect of acetylcholine has led to the identification 30 years ago of nitric oxide (NO) as a major endogenous local regulator of vascular tone. When the ability of endothelial cells to produce NO is blunted, the ensuing vascular dysfunction sets the stage for the occurrence ...

T inventory-routing problem (IRP) dates back 30 years. It can be described as the combination of vehiclerouting and inventory management problems, in which a supplier has to deliver products to a number of geographically dispersed customers, subject to side constraints. It provides integrated logistics solutions by simultaneously optimizing inventory management, vehicle routing, and delivery sc...