There is a growing concern that the velocity of the DT-ice pellets being proposed to fuel ITER will not have the velocity to effectively penetrate through the pedestal of the plasma edge, because with velocities of only 300 m/s, high field side launched pellets will only penetrate to € r /a = 0.90, which may not be adequate for fueling. The likelihood of increasing the pellet velocity is proble...

The aim of this study was to prepare a solid dispersion formulation of curcumin to enhance its solubility, dissolution rate, and oral bioavailability. The formulation was prepared with d-α-tocopheryl polyethylene glycol 1000 succinate (TPGS) and mannitol using solvent evaporation and freeze-drying methods, which yielded a solid dispersion composed of curcumin, TPGS, and mannitol at a ratio of 1...

Isolated from Annona squamosa L, Annonaceous acetogenins (ACGs) exhibit a broad range of biological properties yet absorbed badly due to the low solubility. Solid dispersion in polyethylene glycol 4000 (PEG 4000) has been developed to increase the solubility and oral absorption of ACGs. The formulation of ACGS-solid dispersion was optimized by a simplex lattice experiment design and carried out...

Aspergillus spp are among the powerful microbes involved in environmental management. The growth of Aspergillus niger varies in the form of pellets to biofilm. Pelleted form of growth has been observed in the media without any support, whereas growth nature has been shifted (pelleted to biofilm form) by incorporating solid support in the medium. Scanning electron microscopy (SEM) has proved to ...

Flurbiprofen is a water insoluble non-steroidal anti inflammatory drug and belongs to BCS Class II categories. Solid dispersion is a technique by which we can improve it water solubility. By the help of fast dissolving formulation we can evaluate the effectiveness of solid dispersion. In this research work the solid dispersion of flurbiprofen with polymer like PVP K25, PVP K30, PVP K29-32, and ...

Minipreparation (MiniPrep) analysis is an essential step for obtaining a recombinant plasmid that carries a DNA insert containing a gene of interest. The most commonly used method for this involves cultivation of transformed Escherichia coli (E. coli) in liquid medium, brief centrifugation for precipitation of bacterial pellets, and subsequent lysis of the pellets. This process is time-consumin...

Lamotrigine is used in the treatment of CNS disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. Lamotrigine belongs to biopharmaceutical classification systems, BCS class II (Low solubility & High permeability). In addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...