BACKGROUND Considering all the couples willing and trying to get pregnant, the incidence of infertility is 15% of which approximately half of the cases are due to the male factors. OBJECTIVES The aim of this study was the investigation of the effects of ubiquinol, reduced form of coenzyme Q10 (Co-Q10), an empiric treatment modality, on sperm parameters in idiopathic subfertility. PATIENTS A...

Early recognition of patients at increased cardiovascular risk is a major challenge. The surface electrocardiogram provides a useful platform and it has been used to propose several indexes. T wave axis abnormality is associated with an increased risk of cardiovascular mortality, independently of other risk factors and can be associated with the presence of the metabolic syndrome (MetS). We ass...

Two haemoglobins have been described that do not contain ac-chains: haemoglobin H (Rigas, Koler & Osgood, 1955, 1956; Gouttas, Fessas, Tsevremis & Xefteri, 1955) consists of four fA-polypeptide chains (Jones, Schroeder, Balog & Vinograd, 1959), and haemoglobin Bart's (Ager & Lehmann, 1958) consists of four yF-polypeptide chains (Hunt & Lehmann, 1959). These two abnormal haemoglobins are now ref...

The fertility or sterility of a male depends on several factors, among which are the chemical constituents of the semen, the number, morphological integrity, motility, metabolism and viability of the spermatozoa. These factors, of course, are interrelated in effecting fertility or probability of fertilization. Although in normal matings the number of spermatozoa in the ejaculate is much greater...

This report presents estimates of the prevalence of heart and other cikculatory conditions of children and ycpuths age 6 through 17 years in the' ioninstitutionalized population of the U.S. Estimatei are based on diagnostic impression data from the direct, standardized examination findings of the Health Examination Surveys among national probability samples representative of the 23.8 children a...

A number of recessive autosomal genes cause male infertility. Male mice homozygous for the blind-sterile (bs/bs) and quaking-sterile (qk/qk) gene mutations are sterile, because they either do not produce any spermatozoa or produce only a few abnormal spermatozoa. Mice lacking the cyclic AMP responsive-element modulator gene are sterile due to failure of spermiogenesis. All these mice, however, ...

BACKGROUND Some studies, but not all, support the hypothesis that trisomy frequency is related to the size of the oocyte pool, with the risk increased for women with fewer oocytes (older ovarian age). We tested this hypothesis by comparing hormonal indicators of ovarian age among women who had trisomic pregnancy losses with indicators among women with non-trisomic losses or chromosomally normal...

Opioid peptides have been reported to have important functions in human reproduction. Indeed, very high concentrations of enkephalins and their degrading enzymes have been reported in human semen. In the present paper, we compare the activity of two enkephalin-degrading enzymes, aminopeptidase N and neutral endopeptidase 24.11, in different fractions of semen from normozoospermic, fertile men a...

Background: Male infertility associated with sperm DNA alteration has raised a new issue in assisted reproduction techniques (ARTs).Methods: It was retrospective analytical study on 250 cases of routine IVF/ICSI performed at Swagat ART Centre from January 2017 to 2020. We divided the patient according fragmentation index (DFI) as normal DFI≤15%, n=95, moderate DFI≤30%, n=89, and high DFI group ...