BACKGROUND Maternal-fetal crosstalk during embryo implantation is complex and regulated by local signaling molecules. Chemokines and their receptors are critical signaling components required for implantation and the process of pregnancy. This study aimed to explore whether human first-trimester trophoblast cells (TCs) were capable of modulating the migration and invasion of human first-trimest...

Cuturable heterotrophic bacterial counts (viable counts: VC) by surface plating on ZoBell medium and total bacterial counts (TC) by epifluorescence microscopy were carried out in sea water off the southwest coast of lndia during the monsoon. TC were three orders of magnitude higher than VC. Pseudomonas/Alteromonas group 1 was dominant in both nearshore and offshore regions. Pigmented bacteria w...

In this paper discusses and evaluates “Optimized Link State Routing Protocol” OLSR routing protocol to better performance. Using OPNET simulator tools for the performance of OLSR routing protocol simulation, create in small network (30 nodes), medium size network (40 nodes) and large network (50 nodes) the complexity of the mobile ad-hoc network. The MPR count,”HELLO”message sent ,routing traff...

BACKGROUND The purpose of this study was to assess the impact of drug abuse treatment in Peru that used the therapeutic community (TC) model. Program directors and several staff members from all study treatment facilities received two to eight weeks of in-country training on how to implement the TC treatment model prior to the follow-up study. METHODS This outcome study involved 33 TC treatme...

Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors have been shown to reduce atherosclerotic lesions in animals; however, the mechanism(s) for this effect remains unclear. Therefore, we used cultured primary human monocyte-derived macrophages (HMMs) to examine the effect of the ACAT inhibitor, avasimibe (CI-1011), during foam cell formation and during cholesterol efflux from established foa...

The thalamocortical (TC) system is a tightly coupled synaptic circuit in which GABAergic inhibition originating from the nucleus reticularis thalami (NRT) serves to synchronize oscillatory TC rhythmic behavior. Zinc is colocalized within nerve terminals throughout the TC system with dense staining for zinc observed in NRT, neocortex, and thalamus. Whole cell voltage-clamp recordings of GABA-evo...

The ethanolic leaf extract of Cymbidium aloifolium (L.) was intended to evaluate the effect on the central nervous system (CNS) using a number of neuropharmacological experimental models in mice. The extract, at the dose of 200 and 400 mg/kg body weight, were shown to have CNS depressant activity by the reduction of locomotor and exploratory activities in the open field and hole cross tests. Th...

Sameterol xinafoate is a selective β2-adrenoceptor agonist used in the treatment of some lung diseases and play a vital role in the regulation of bone mass and bone turnover. Tc-salmeterol was formulated for the development of a novel potential diagnostic bone imaging agent with excellent biological properties. Factors influencing the labeling yield such as salmeterol xinafoate amount, pH of th...

We present a novel methodology for determining the transport of technetium-99m, a γ-emitting metastable isomer of (99)Tc, through quartz sand and porous media relevant to the disposal of nuclear waste in a geological disposal facility (GDF). Quartz sand is utilized as a model medium, and the applicability of the methodology to determine radionuclide transport in engineered backfill cement is ex...