PURPOSE The purpose of this study was to examine the tumor specificity, cytotoxicity, and granulocyte macrophage colony-stimulating factor expression of CG0070, a conditionally replicating oncolytic adenovirus, in human bladder transitional cell carcinoma (TCC) cell lines and determine its antitumor efficacy in bladder TCC tumor models. EXPERIMENTAL DESIGN Virus yield and cytotoxicity assays ...

We prove that both the synchronous data ow language Lustre restricted to nite value types and the synchronous state oriented language Argos are embedded in the synchronous paradigm Timed Concurrent Constraint (tcc). In fact, for each of the two languages we provide a tcc language encoding it compositionally w.r.to the structure of programs. Moreover, we prove that the \strong abortion" mechanis...

Thermal Contact Conductance (TCC) between an exhaust valve and its seat is one of the important parameters to be estimated in an internal combustion engine. An experimental study presented here to acquire temperature in some interior points to be used as inputs to an inverse analysis. An actual exhaust valve and its seat are utilized in a designed and constructed setup. Conjugate Gradient Metho...

Triclocarban (3,4,4'-trichlorocarbanilide, TCC) is a widely used antibacterial agent in personal care products and is frequently detected as an environmental pollutant in waste waters and surface waters. In this study, we report novel reactive metabolites potentially formed during biotransformation of TCC. The oxidative metabolism of TCC has been predicted using an electrochemical cell coupled ...

OBJECTIVE The standard surgical treatment of upper tract TCC remains nephroureterectomy with excision of a cuff of bladder. However, laparoscopic nephroureterectomy (LNU) has been shown to be associated with reduced perioperative morbidity, a shorter hospital stay, and a reduced requirement for transfusion than open nephroureterectomy (ONU). The objective of this article is to review experience...

BACKGROUND Tai Chi is the Chinese traditional medicine exercise for mind-body health. The objective of this study is to investigate the effect of Tai Chi Chuan (TCC) exercise on the proliferative and cytolytic/tumoricidal activities of peripheral blood mononuclear cells (PBMCs) in postsurgical non-small cell lung cancer (NSCLC) patients. METHODS Patients (n = 27) were randomly divided into th...

We report on cytotoxic effects of bcl-2 and bcl-xL antisense-oligodeoxynucleotides (AS-ODNs) in benign urothelial and transitional cell carcinoma (TCC) cell lines. The benign urothelial cell line (UROtsa) and four TCC cell lines (UM-UC-3, RT 112 , HT 1197 and T 24/83) were incubated with bcl-2 and bcl-xL AS-ODNs and cell mortality rates were assessed. Bcl-2 and bcl-xL AS-ODN treatment resulted ...

Myelin oligodendrocyte glycoprotein (MOG) is an encephalitogenic myelin protein and a likely autoantigen in human multiple sclerosis (MS). In this work, we describe the fine specificity and cytokine profile of T cell clones (TCC) directed against MOG in three nuclear families, comprised of four individuals affected with MS and their HLA-identical siblings. TCC were generated from PBMC by limiti...

Introduction: Transitional cell carcinomas (TCC) of the upper urinary tract constitute only 7% of urothelial carcinomas. The majority of upper urinary tract TCC arises from the renal pelvis, followed by the ureter. The majority of the patients are presented with microscopic or macroscopic haematuria, flank pain, or symptoms due to metastasis; however, it can be asymptomatic in 10-15%. Case pre...