Human health risks associated with the consumption of three shellfish (<i>Penaeus monodon, Crassostrea rhizophorae</i>, and <i>Tympanostomus fuscatus</i>) harvested from Buguma, Krakrama, Bonny Rivers in Niger Delta region were evaluated this study. The bioaccumulation potential toxic elements (PTEs) [Arsenic (As), Cadmium (Cd), Chromium (Cr), Lead (Pb), Nickel (Ni)] was...

This interaction profile discusses and evaluates the evidence for joint toxic action among lead, manganese, zinc, and copper. The interaction profile recommends how to incorporate concerns about possible interactions or additivity into public health assessments of hazardous waste sites where people might be exposed to mixtures of these chemicals. The profile recommends using endpoint-specific h...

The post-translational farnesylation of proteins serves to anchor a subset of intracellular proteins to membranes in eukaryotic organisms and also promotes protein-protein interactions. Inhibition of protein farnesyltransferase (PFT) is lethal to the pathogenic protozoa Plasmodium falciparum. Parasites were isolated that were resistant to BMS-388891, a tetrahydroquinoline (THQ) PFT inhibitor. R...

Gills and muscles of Tilapia fish from Naik lake of Nagpur city were estimated for heavy metals (Zinc, Lead, Nickel, Copper and Cadmium) using inductively coupled plasma optical emission spectrometry (ICP-OES). Results showed higher concentrations of heavy metals in gills than in muscles of tilapia fish. Trends of heavy metal concentrations in gills and muscles of tilapia fish were found Zn > P...

Introduction. Fresh vegetables are of a great value and the most common foods in human diet around world. They contain minerals, vitamins, antioxidants, antimetabolites, protein, carbohydrates, water. However, they major source heavy metals, which both essential toxic metals over wide range concentrations. The study sites serve as regional commercial center, where such cabbages, onions, carrots...

N-Acetylation of the tetrahydroquinoline (THQ) core of a series of μ-opioid receptor (MOR) agonist/δ-opioid receptor (DOR) antagonist ligands increases DOR affinity, resulting in ligands with balanced MOR and DOR affinities. We report a series of N-substituted THQ analogues that incorporate various carbonyl-containing moieties to maintain DOR affinity and define the steric and electronic requir...

a risk assessment study was conducted to predict the expected hazardous influence on the ecosystem resulted from urbanization and industrialization activities at helwan area, egypt. to achieve these goals, soils, plants and water samples were collected from helwan area, and their total concentrations of inorganic contaminants (cd, cr, co, cu, fe, mn, ni, pb, and zn) and organic pollutants; such...

Concentration of heavy metals (Cr, Ni, Cu, Zn, As, Cd, Pb and Hg) in cabbages potatoes were determined the potential human health risks due to consumption vegetables have been estimated. Mean concentrations Zn (134.0 + 5.62 mg/kg), As (0.12 0.01 mg/kg) Cd (0.32 from Biological Lagoon area as well (103.0 8.34 (0.14 (0.31 Boicha stream above safety limits FAO/WHO. Likewise, mean (0.24 0.03 (0.35 ...

In this study, a total of 135 Chinese mitten crab (Eriocheir sinensis) samples were collected from four major crab-producing provinces (Jiangsu, Hubei, Anhui, and Liaoning) in China. The content 24 trace elements the edible parts crabs was determined by inductively coupled plasma mass spectrometry (ICP-MS). addition, different compared, heavy metal levels exceeding standard evaluated. Twenty me...