Lipocalin-type prostaglandin D synthase (L-PGDS) is a member of the lipocalin superfamily, which is composed of secretory transporter proteins, and binds a wide variety of small hydrophobic molecules. Using this function, we have reported the feasibility of using L-PGDS as a novel drug delivery vehicle for poorly water-soluble drugs. In this study, we show the development of a drug delivery sys...

BACKGROUND AND OBJECTIVES Intravenous immunoglobulin-SN (IVIG-SN) is a new human immunoglobulin product. Its safety is ensured by pathogen-elimination steps comprising solvent/detergent treatment and a nanofiltration process. This multicenter clinical study was designed to evaluate the efficacy and safety of combined aspirin and high-dose IVIG-SN therapy in pediatric patients with Kawasaki dise...

This paper studies a novel audio segmentation-by-classification approach based on Factor Analysis (FA) with a channel compensation matrix for each class and scoring the fixed-length segments as the log-likelihood ratio between class/no-class. The system described here is designed to segment and classify the audio files coming from broadcast programs into five different classes: speech (SP), spe...

Cystatin SN has been considered to be involved in human cancer, but its clinical significance in non-small cell lung cancer (NSCLC) has not been elucidated. The aim of this study was to evaluate the clinical value of Cystatin SN expression in patients with surgically resected NSCLCs. A retrospective analysis of 174 patients with surgically resected NSCLCs from April 2002 to March 2005 was perfo...

High time resolution spectroscopic observations of the ultra-compact helium dwarf nova ‘SN 2003aw’ in its quiescent state at V ∼ 20.5 reveal its orbital period at 2027.8±0.5 seconds or 33.80 minutes. Together with the photometric “superhump” period of 2041.5±0.5 seconds, this implies a mass ratio q≈ 0.036. We compare both the average and time-resolved spectra of ‘SN 2003aw’ and SDSS J124058.03−...

The dithio-carbamate anions in the title compound, [Sn(C(4)H(9))(2)(C(5)H(10)NS(2))(2)], chelate to the Sn(IV) atom, which is six-coordinated in a skew-trapezoidal-bipyramidal geometry. The mol-ecule lies across a twofold rotation axis. The crystal studied was a non-merohedral twin, the ratio of the twin components being 0.82 (1):0.18 (1).

We have employed ab initio molecular dynamics to investigate the equilibrium geometries, energetics, and the nature of bonding in mixed Li-Sn clusters. Our studies reveal that a small percentage of Sn in Li-rich clusters introduces significant changes in the equilibrium geometries. It is also seen that the geometries of Sn-rich clusters are influenced by the Sn10 motif. Analysis of the nature o...

Background & Aims of the Study: Due to the rapid industrial development in Khuzestan province of Iran during recent years, this study was performed to analyze the variation of metals concentrations (Mg, Mn, Ni, and Sn) in soil samples of Ahvaz II Industrial estate during the spring season of 2013. Materials & Methods: In this experimental study, 27 topsoil samples were co...

We describe the Neutrino Spectrum and detection for SN II sources. We discuss the effects of neutrino mixing in the SN II. A new analysis of SN1987A is described. We discuss the possible detection of the diffuse relic SN II flux. Finally we discuss a new detection concept, OMNIS, for and and detection and compare with μ 2 other present and future SN detectors.

BACKGROUND The personality as a system of genetically predetermined features is responsible for modifying relations between an individual's genotype and phenotype. The key element linking personality with facial morphology is the muscular system. OBJECTIVES The aim of this study was to investigate the association between facets of the five-factor personality model (FFM) domains and both the m...