Rats of the Dark Agouti strain were trained on delayed alternation under conditions that should encourage egocentric working memory. In two experiments a T-maze was set within a cross-maze so that different arms could be used for the sample and test runs. The maze had high opaque side-walls, and testing was conducted in low light levels so that distal visual cues might be eliminated. By rotatin...

The present study examined the performance of rats with neurotoxic lesions centred in the thalamic nucleus medialis dorsalis on standard and modified versions of the eight arm radial maze test. In Experiment 1, the thalamic lesions produced a borderline deficit in acquisition of the standard task, but subsequently had no effect when a delay was interposed after the first four arms had been ente...

Laboratory mazes were used to study spatial-learning capabilities in cuttlefish (Sepia offcinalis), using escape for reinforcement. In preliminary observations, cuttlefish in an artificial pond moved actively around the environment and appeared to learn about features of their environment. In laboratory experiments, cuttlefish exited a simple alley maze more quickly with experience and retained...

Rats with cytotoxic lesions of the rostral pole of the thalamic reticular nucleus were compared with surgical control animals on a series of spatial learning and memory tests. While evidence was found for an initial, transient impairment on forced-choice alternation in a T-maze, this rapidly disappeared, and overall performance was unaffected. Subsequent experiments found no evidence that lesio...

Reinforcing properties of serotonin administration to the lateral hypothalamus were tested on the experimental model of the T-maze learning in 19 rats. The results did not definitely prove either positive or negative reinforcement produced by the central serotonergic stimulation, although the rats modified their behavior in the maze in the response to intrahypothalamic serotonin. It seems that ...

The tendency to select T-maze arm that has been changed in brightness between two consecutive trials was investigated under different experimental conditions. In trial 1 rat was confined in maze stem for 10 min and allowed to observe black-and-white arms through transparent partitions. In trial 2 the color of one arm was changed, so that both arms were alike (either white or black) and the rat ...

Background and Objective: Crassocephalum bauchiense Hutch is a species of flowering plant from the Asteraceae family. It’s used in traditional medicine for treatment brain disorders including epilepsy, depression anxiety. This study evaluated anxiolytic effects aqueous extract its possible mechanism action. Materials Methods: The (25, 50, 100 200 mg/kg) were administered orally to mice one hour...

Memory retrieval requires both accuracy and speed. Olfactory learning of the fruit fly Drosophila melanogaster serves as a powerful model system to identify molecular and neuronal substrates of memory and memory-guided behavior. The behavioral expression of olfactory memory has traditionally been tested as a conditioned odor response in a simple T-maze, which measures the result, but not the sp...