AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...

AbstractGene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. One promising form of gene delivery system (DDS) is liposomes. The success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. Liposomal gene delivery systems...

abstractgene therapy is a therapeutic approach to deliver genetic material into cells to alter their function in entire organism. one promising form of gene delivery system (dds) is liposomes. the success of liposome-mediated gene delivery is a multifactorial issue and well-designed liposomal systems might lead to optimized gene transfection particularly in vivo. liposomal gene delivery systems...

Hazenberg BPC. Clinical approach of patients with systemic amyloidosis Amyloidosis is the name of diseases characterised by deposition of protein fibrils with a beta-sheet structure. This beta-sheet structure generates affinity of amyloid for Congo red dye and is resistant to proteolysis. The main three types of systemic amyloidosis are AA (related to underlying chronic inflammation), AL (relat...

Amyloidosis is a group of diseases, all characterised by deposition of protein fibrils with a beta-sheet structure. This structure generates affinity of amyloid for Congo red dye and is resistant to proteolysis. Three types of systemic amyloidosis are important for the clinician: AA (related to underlying chronic inflammation), AL (related to underlying monoclonal light chain production) and AT...

The paper presents issues related to a systemic approach for the development of foresight studies. Necessary steps are identified and most common methods are analyses, with their weakness and straits. The authors make a point in underlining that foresight is not about methods, but about management of change. Four metastrategies of change are described. Change as an organizational process has be...

paragangliomas are extra-adrenal counterparts of pheochromocytomas and are found at various anatomical sites such as the retroperitoneum, mediastinum, jugular foramen and carotid bifurcation, the latter two fonns being coined as chemodectomas. the vertebral column, especially the llullbar zone, is one of the rarest sites to be involved by paragangliomas. these lesions may have secretory functio...

introduction : due to the increased prevalence of medically compromised patients who require dental treatments, it is a crucial task for dentists and dental specialists to prepare themselves for emergent professional situations. this study was performed to determine the prevalence of different medical problems among a population of patients admitted to a dental educational center. materials and...

secondary systemic vasculitis and nonbacterial endocarditis are rare events. we report a case presented with different manifestations of underlying malignancy such as systemic vasculitis, non bacterial endocarditis and dic (disseminated intravascular coagulopathy). efforts to find the source of malignancy was unsuccessful and due to patient's unwillingness for further evaluation, finally under ...