نتایج جستجو برای: synthase

تعداد نتایج: 83580  

Journal: :Current Opinion in Chemical Biology 2021

Sugar nucleotide–modifying enzymes of the short-chain dehydrogenase/reductase type use transient oxidation–reduction by a tightly bound nicotinamide cofactor as common strategy catalysis to promote diverse set reactions, including decarboxylation, single- or double-site epimerization, and dehydration. Although basic mechanistic principles have been worked out decades ago, finely tuned control r...

2016
Erland Arning Brian D Lowes Matthew RG Taylor Xingli Meng Raphael Schiffmann Teodoro Bottiglieri

BH4: Tetrahydrobiopterin; BH2: Dihydrobiopterin; NOS: Nitric Oxide Synthase; eNOS: endothelial Noxide Synthase; nNOS: Neuronal Nitric Oxide Synthase; iNOS: Inducible Nitric Oxide Synthase; CAD: Coronary Artery Disease; LC-MS/MS: Liquid Chromatography and Tandem Mass Spectrometry; GTCH1: Guanine Triphosphate Cyclohydrolase; NOS3: Nitrous Oxide Synthase 3 – Endothelial; QDPR: Quinoid Dihydropteri...

2011
Jean-Eric Alard Sophie Hillion Loïc Guillevin Alain Saraux Jacques-Olivier Pers Pierre Youinou Christophe Jamin

BACKGROUND Heat shock protein (hsp) 60 that provides "danger signal" binds to the surface of resting endothelial cells (EC) but its receptor has not yet been characterized. In mitochondria, hsp60 specifically associates with adenosine triphosphate (ATP) synthase. We therefore examined the possible interaction between hsp60 and ATP synthase on EC surface. METHODOLOGY/PRINCIPAL FINDINGS Using F...

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