نتایج جستجو برای: synovial sarcoma
تعداد نتایج: 88112 فیلتر نتایج به سال:
primary cardiac sarcomas are rare clinical entities with an incidence rate of 0.0001% in collected autopsy series and are regarded as very aggressive tumors. we herein describe a 21-year-old woman presenting with syncope, dyspnea, and abdominal distention. she suffered from massive ascites, plural effusion, and liver congestion demonstrated by abdominal sonography and chest x-ray. transthoracic...
PURPOSE To evaluate the characteristics of highly malignant soft tissue sarcoma of the extremity with a delayed diagnosis. MATERIALS AND METHODS The clinical and radiological characteristics of 18 cases of highly malignant soft tissue sarcomas of the extremity with a delayed diagnosis were determined. RESULTS Ten men and eight women of mean age 44.8 years (range, 15-79 years) were included ...
Key-words Disease name Definition/Diagnostic criteria Differential diagnosis Etiology Clinical description Diagnostic methods Prognostic factors Epidemiology Management Unresolved questions References
AIMS Malignant peripheral nerve sheath tumour (MPNST) is an unusual sarcoma of the heart and should be differentiated from other spindle cell sarcomas. METHODS AND RESULTS We combined morphological, immunohistochemical and cytogenetic techniques in the differential diagnosis, particularly from monophasic synovial sarcoma. The tumour consisted of dense fascicles, alternating with hypocellular,...
Akt activation by the IGF-1 receptor (IGF-1R) has been posited to be a mechanism of intrinsic resistance to mTORC1 inhibitors (rapalogues) for sarcomas. Here we show that rapamycin-induced phosphorylation of Akt can occur in an IGF-1R-independent manner. Analysis of synovial sarcoma cell lines showed that either IGF-1R or the PDGF receptor alpha (PDGFRA) can mediate intrinsic resistance to rapa...
Synovial sarcoma (SS) is a rare type of high-grade soft tissue that accounts for 5% to 10% all tumors. It primarily affects the arms and legs. The rate lymph node metastases in synovial 3% 7%. They are locally aggressive have higher metastatic potential. overall prognosis patients poor due systemic metastasis. Immunohistochemistry molecular studies indispensable diagnosis these We present you c...
BACKGROUND Synovial sarcoma is a mesenchymal neoplasm that accounts for around 10% of all soft tissue sarcomas. The diagnosis of synovial sarcoma can be a challenging task, particularly with small biopsy specimens. AIM We investigated transducer-like enhancer of split 1 (TLE1), monoclonal antibody, expression by immunohistochemical analysis in a group of 74 synovial sarcoma cases, 20 cases of...
Abstract Synovial sarcomas are rare malignant mesenchymal soft tissue tumors. We presented the case of a 53-year-old woman patient presenting with acute deep vein thrombosis, later diagnosed as synovial sarcoma femoral wall. The tumor was identified through cross-sectional magnetic resonance angiography and computed tomography, followed by ultrasound-guided core biopsy. report emphasized import...
Synovial sarcoma (SS) is a rare but distinctive soft tissue sarcoma (STS) that displays epithelial differentiation. It consists of 5% to 10% of STSs. Surgery is the mainstay of treatment to prevent local recurrence and maximam five-year survival rate is 40 %. Recently, SS was noted to have increased post chemotherapy survival time and the sensitivity of SS to ifosfamide-based chemotherapy h...
UNLABELLED INTRODUCTION Synovial sarcoma is a high-grade, soft-tissue sarcoma that most frequently is located in the vicinity of joints, tendons or bursae, although it can also be found in extra-articular locations. Most patients with synovial sarcoma of the hand are young and have a poor prognosis, as these tumors are locally aggressive and are associated with a relatively high metastasis r...
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