One of the main criteria for the diagnosis of cystic fibrosis of the pancreas is the presence of a raised sweat sodium level in the patient (Di Sant' Agnese, Darling, Perera, and Shea, 1953). The standard method of using pilocarpine iontophoresis to produce sweat (Gibson and Cooke, 1959), and estimating the sodium present by conductivity or flame photometry, is a workable technique but has some...

The volume of sweat produced by axon reflex stimulation using acetylcholine was measured in one foot each of 35 control subjects and 52 feet of 37 diabetic patients (28 with neuropathic ulceration, 11 with Charcot arthropathy, nine with somatic neuropathy but no foot lesion and four with no evidence of somatic neuropathy). In controls, the volume of sweat was greater in males than females. A fl...

A 3 1/2 year old girl presented with failure to thrive and a five month history of diarrhoea and recurrent cough. The results of sweat sodium tests suggested a diagnosis of cystic fibrosis; but atypical organisms were found (Haemophilus influenzae, Candida albicans, but no Staphylococcus aureus), she failed to respond to treatment, and her sweat sodium concentrations fell in response to fludroc...

The purpose of this study was to determine the effect of active heat acclimation on the sweat osmolality and sweat sodium ion concentration vs. sweat rate relationship in humans. Eight healthy male volunteers completed 10 days of exercise in the heat. The mean exercising heart rate and core temperature were significantly decreased (P < 0.05) by 18 beats/min and 0.6 degrees C, respectively, foll...

INTRODUCTION Pancreatitis is a rare manifestation of cystic fibrosis (CF) and may rarely be the presenting symptom in adolescent or adult patients with CF. We report a case of a 4 year-old female who initially presented with recurrent pancreatitis, a normal sweat test, and a diagnosis of pancreas divisum. She was subsequently diagnosed with cystic fibrosis at the age of 6 years, despite normal ...

Human shidies: A: The influence of the underwear fabric material on sweat production, evaporation, and sweat accumulation in a two-layer clothing system (I,d =.0.25 m2.K-W-') was studied (n=8). Five different fiber type materials (cotton (C), wool 0, polypropylene (P), and two polyesters with different finish (Po l , P02)) were tested in the underwear. The 2-hour test comprised a twice repeated...

BACKGROUND Sodium (Na(+)) intake during exercise aims to replace the Na(+) lost by sweat to avoid electrolyte imbalances, especially in endurance disciplines. However, Na(+) needs can be very different among individuals because of the great inter-individual variability in sweat electrolyte concentration. The aim of this investigation was to determine sweat electrolyte concentration in a large g...