The treatment of supraglottic carcinoma remains a controversial issue. Five accepted surgical and non-surgical oncological treatments have been currently established: standard horizontal supraglottic laryngectomy (HSL), supraglottic CO2 laser microsurgery (TLM), transoral robotic surgery, radiotherapy alone and radiotherapy in combination with chemotherapy. Some studies have shown that complica...

Cursul Na]ional de Ghiduri [i Protocoale în ATI As anesthesiologists we spend a respectable part of our career maintaining the airway. Theoretically, every anesthesiologist should be familiar with, and well practiced in a variety of the airway techniques that are available, so that when an airway problem occurs, it can be managed with a solid armamentarium of information and experience. However...

OBJECTIVE To constitute an animal model of laryngeal allergy and evaluate the laryngeal effects of inhaled corticosteroids and ß2-agonists on the laryngeal mucosa in an allergic rat model. STUDY DESIGN Prospective randomized. SETTING The Experimental Medical Research Institute (DETAE) at Istanbul University. SUBJECTS AND METHODS Wistar Albino rats (n = 32) were sensitized with ovalbumin. ...

Tumor-associated macrophages (TAMs) can elicit contrasting effects on tumor progression, depending on different tumor microenvironment. This study aimed to explore the correlation between TAM infiltration and clinicopathologic characteristics, metastasis, and prognosis of supraglottic laryngeal carcinoma. TAMs in intratumoral and peritumoral regions of 84 specimens of supraglottic laryngeal car...

BACKGROUND Current management of laryngeal malignancies is associated with significant morbidity. Application of minimally invasive transoral techniques may reduce the morbidity associated with traditional procedures. The purpose of this study was to present our investigation of the utility of a novel flexible robotic system for transoral supraglottic laryngectomy and total laryngectomy. METH...

OBJECTIVE This study aims to evaluate the production of interferon-gamma and interleukin-10 by stimulated peripheral blood mononuclear cells isolated from patients with supraglottic laryngeal cancer before and after surgical treatment. METHODS Fourteen patients with advanced supraglottic laryngeal cancer were studied. Cultures of peripheral blood mononuclear cells isolated during the preopera...

These guidelines provide a strategy to manage unanticipated difficulty with tracheal intubation. They are founded on published evidence. Where evidence is lacking, they have been directed by feedback from members of the Difficult Airway Society and based on expert opinion. These guidelines have been informed by advances in the understanding of crisis management; they emphasize the recognition a...

We report on a 69-year-old patient with post definitive radiochemotherapy (until 04/2013) and tracheostomy closure for T3N2M0 supraglottic laryngeal carcinoma. There is markedly limited elevation cutaneous radiation syndrome, scarring retraction in the area of former pronounced dysphonia.