Introduction Parkinson’s disease (PD) is characterized by loss of dopaminergic neurons in the substantia nigra (SN), but its etiology remains poorly understood (1). In vivo H MRS may provide a noninvasive alternative to culture, animal model and post-mortem studies that are more commonly utilized to understand the pathogenesis of PD. However, due to its small size, the MRS investigation of the ...

Parkinson's disease (PD) was first described by James Parkinson in 1817. He noted the complex nature of this condition and that non-motor symptoms (NMS) underpinned the classic motor symptoms of PD. The concept of what PD is has therefore undergone substantial changes and it is now recognised that PD is a combined motor and non-motor syndrome and NMS are present during the prodromal phase of PD...

The Sulawesi black-crested macaque (Macaca nigra) is an endemic primate of North that categorized as critically endangered (IUCN 2015). Endoparasite contributes to the decline M.nigra. Therefore, this study aims determine prevalence endoparasites in (M. nigra). We collected 80 fresh fecal samples representing all sex from two habituated groups. analyzed them using direct examination technique (...

Alergol Inmunol Clin, December 1999 Vol. 14, No 6, pp. 398-401 The blackberry (Morus nigra, Rubus fruticosus) (Fig. 1) is the fruit of the blackberry bush, a wild-occurring bush of the Rosaceae family, genus Rubus. A number of proteins from fruits of this family have been implicated in allergic processes, both independently and in association with pollenosis. There have been reports of asthma, ...

Transient focal cerebral ischaemia can cause neuronal damage in remote areas, including the ipsilateral thalamus and subsutantia nigra, as well as in the ischaemic core. In the present study, we investigated long-term changes in the ipsilateral substantia nigra from 1 up to 20 weeks after 90 min of transient focal cerebral ischaemia in rats, using tyrosine hydroxylase (TH), neuronal nuclei (Neu...

Weaver is a spontaneous mutation in mice characterized by the postnatal loss of external granule cells in the cerebellum and dopaminergic neurons of the midbrain, especially in the substantia nigra. We have shown previously that natural cell death with the morphology of apoptosis occurs in the substantia nigra of normal rodents during postnatal development. We therefore sought to determine whet...

OBJECTIVE to define the quantitative characteristics of cell structures in the substantia nigra pars compacta of neurologically healthy elderly people (men and women). MATERIAL AND METHODS Autopsy brain materials from neurologically healthy men and women who had died from intercurrent diseases at the age of 72 to 87 years were examined for quantitative characteristics of the substantia nigra ...

The study was done to assess the phytochemicals (flavonoids, terpenoids, saponins, tannin, alkaloids, and phenol) in different parts (root, stem, and leaves) of Ballota nigra and correlated it to inhibition of microbes (bacteria and fungi), protozoan (Leishmania), and heavy metals toxicity evaluation. In root and stem flavonoids, terpenes and phenols were present in ethanol, chloroform, and eth...

The concept of substantial equivalence, introduced for the risk assessment of genetically modified (GM) food, is a reducing concept because it ignores the context in which these products have been produced and brought to the consumer at the end of the food chain. Food quality cannot be restricted to mere substance and food acts on human beings not only at the level of nutrition but also through...