Inhibition of metabolism by structural analogs of metabolites is one of the newer concepts of chemotherapy. It seems possible that this concept might be applied to cancer by use of structural analogs of glucose to inhibit the glycolysis of the tumor cell, since tumor tissue in contrast to most normal tissues possesses the ability to glycolyze glucose at a high rate both anaerobically and aerobi...

I com mend the ex cel lent work of Dr Ken-nedy, Dr Lam, and the work ing group that pro vided the Clin i cal Guide lines for the Treat ment of De pres sive Dis or ders (1). This let ter is to pro vide up dated in for ma-tion from a sys tem atic re view of short-term dy namic psychotherapies (STDPs) cur rently be ing con ducted under the Cochrane Col lab o ra tion (2) and to dem on strate that c...

The De part ment's field of re search cov ers the en tire pro cess of plan ning, con struc tion and man age ment, from con cep tuali sation to de mo li tion and re use. Re search stud ies in clude tech nol ogy as well as so cial stud ies, hu man i ties and arts. These can be stud ied in an in ter-dis ci plin ary and multi-dis ci plin ary way, or more in-depth stud ies can be car ried out within...

The purpose of this study was to evaluate the traction characteristics of four different stud configurations on 2-Star, third generation artificial soccer turf during cutting movements. Traction, among others, characterizes player-surface interaction and is a key for top level performance in soccer. The concept of this study involves a combination of performance, subjective-sensory and biomecha...

BACKGROUND Public health research provides evidence for practice across fields including health care, health promotion and health surveillance. Levels of public health research vary markedly across European Union (EU) countries, and are lowest in the EU's new member states (in Central and Eastern Europe and the Mediterranean). However, these countries now receive most of the EU's Structural Fun...

In vitro models are invaluable tools for studying cell behavior in a highly controlled setting. Cell and tissue culture models of the nervous system can be utilized to elucidate neurobiological phenomena that are difficult to observe, manipulate, or measure in vivo. In the context of biomechanics, culture models that accurately mimic specific brain features can be used to determine tissue prope...

The time deveIopment for the intermolecular transfer of electronic energy has, until recently, been studied by measurements of the molecular light emission. The observation of the transfer process has been limited to times of the order of the fluorescent lifetime, and naturally to systems which emit light $#. With the application of the picosecond method 121, which utilizes absorption, rather t...

Through the examination of 11 intact interuniversity research project teams, this study examines the relationship between team leaders, team members, their communication networks (represented as structural holes), and performance. The study shows that in the conduct of their work, the team leaders bridged more structural holes than team members. Although team leaders demonstrated a higher level...

Abstract Light-gauge steel framed (LSF) wall systems of low- and mid-rise buildings are made cold-formed studs tracks lined with sheathing material such as gypsum plasterboard. The stiffness provided by can be idealised into three main components, namely, in-plane, out-of-plane rotational stiffness. Idealised in-plane has been used commonly in the numerical analytical studies stud walls. Experi...