In this paper a new fuzzy modeling algorithm is proposed and a new inference schema is developed for fuzzy reasoning that suits to the proposed approach

Methods for identifying the structure of dynamic mathematical models for water quality by reference to experimental field data are discussed . The context of the problem of model structure identification is described by briefly reviewing the steps involved in the overall process of system identification. These steps include experimental design; choice of model type; model structure identificati...

Ricin is a potent cytotoxin which has been used widely in the construction of therapeutic agents such as immunotoxins. Recently it has been used by governments and underground groups as a poison. There is interest in identifying and designing effective inhibitors of the ricin A chain (RTA). In this study computer-assisted searches indicated that pterins might bind in the RTA active site which n...

Proper orthogonal decomposition (POD) is applied to the direct numerical simulation (DNS) of a turbulent boundary layer performed by Wu & Moin (2010), and the resulting POD modes of various scales are examined. The modes include structures resembling those observed in instantaneous flow fields, such as large-scale motions of streamwise velocity with ramp-like wall-normal growth. Other modes cor...

The present paper addresses the experimental identification of a nonlinear space structure, the SmallSat spacecraft developed by EADS-Astrium. The nonlinear component comprises an inertia wheel mounted on a support, the motion of which is constrained by eight elastomer plots and mechanical stops. Robust techniques are applied to measured data to detect, characterise and quantify nonlinear behav...

This paper investigates automatic identification of Information Structure (IS) in texts. The experiments use the Prague Dependency Treebank which is annotated with IS following the Praguian approach of Topic Focus Articulation. We automatically detect t(opic) and f(ocus), using node attributes from the treebank as basic features and derived features inspired by the annotation guidelines. We pre...

Several recent studies show that inhibition of the hepatic transport proteins organic anion-transporting polypeptide 1B1 (OATP1B1) and 1B3 (OATP1B3) can result in clinically relevant drug-drug interactions (DDI). To avoid late-stage development drug failures due to OATP1B-mediated DDI, predictive in vitro and in silico methods should be implemented at an early stage of the drug candidate evalua...

Genetic programming can be used to evolve an algebraic expression as part of an equation representing measured input-output response data. Parts of the nonlinear differential equations describing a dynamic system are identified along with their numerical parameters using genetic programming. The results of several such optimisations are analysed to produce a nonlinear physical representation of...

Many networks can be usefully decomposed into a dense core plus an outlying, loosely connected periphery. Here we propose an algorithm for performing such a decomposition on empirical network data using methods of statistical inference. Our method fits a generative model of core-periphery structure to observed data using a combination of an expectation-maximization algorithm for calculating the...

With the expansion of offender/arrestee DNA profile databases, genetic forensic identification has become commonplace in the United States criminal justice system. Implementation of familial searching has been proposed to extend forensic identification to family members of individuals with profiles in offender/arrestee DNA databases. In familial searching, a partial genetic profile match betwee...