The study of the human mind embodied in cognitive science strives to understand the nature of the abstract representations and computational processes responsible for our ability to reason, speak, perceive and interact with the world, etc. In addition, a commitment to a materialist resolution of the mind-body problem requires that we search for the manner in which these representations and proc...

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We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled, in many of our cases the disorder-to-order transition occurs upon complex formation and can be localized to binding interfaces. Moreover, analysis ...

Spatial cognition research has recently made much progress in understanding the cognitive representations and processes underlying human wayfinding. Many theoretical assumptions about the concept of landmark salience have been established. In this context it is important to define perceptual (or visual) and structural landmark salience. Structural salience is defined as the position of a landma...

This paper describes a study evaluating increase in design strength, performance and capacity when including bridge parapets in a bridge analytical model. Traditionally, concrete parapets are treated solely as superimposed dead load in an overall bridge structural design. Parapets are detailed from a safety standpoint to resist impact forces from vehicle loading. However, in the global design m...

This paper draws together two methodologies for the detection of bit replacement steganography: the principle of maximum likelihood, which is statistically well-founded but has lead to weak detectors in practice, and so-called structural detection, which is sensitive but lacks optimality and can suffer from complicated exposition. The key novelty is to extend structural analysis to include a hy...

ion over Structural Types (1) Now consider encapsulating the equations: bar = sigrel (u, y) where foo ⋄ (u, v ,w) foo ⋄ (w , u + x , v + y) The equations of the body of bar needs to be partitioned into • Local Equations: equations used to solve for the local variables • Interface Equations: equations contributed to the outside Type-Based Structural Analysis for Modular Systems of Equations – p....

Recent advances in spectroscopic methods allow the identification of minute fluctuations in a protein structure. These dynamic properties have been identified as keys to some biological processes. The consequences of this structural flexibility can be far-reaching and they add a new dimension to the structure-function relationship of biomolecules. Nuclear Magnetic Resonance (NMR) spectroscopy a...

Analyzing protein-RNA binding structures depends on a significant quantity of manual work. Therefore, the protein-RNA binding structures are generally studied individually or on a small-scale. The task of analyzing the protein-RNA binding structures manually becomes increasingly difficult as the complexity and number of protein-RNA binding structures increase. We have developed a set of algorit...

Measuring is a key issue in any software-related activity. In the context of the i* framework, we are implementing Measufier, a prototype for measuring i* diagrams in terms of properties that may be derived from their structure (structural measures). The prototype works over i* diagrams represented by the iStarML interchange format, and provides some facilities for managing measures' catalogues...