Background: Previous preclinical findings reported that Strontium ranelate increases the secretion of osteoprotegerin (OPG) protein as well as mRNA levels and down-regulates both RANKL protein and mRNA expression in primary human osteoblasts; this increase in the OPG/RANKL ratio is known to negatively affect osteoclastogenesis. Objectives: The objective of the present study is to assess the eff...

This work reports the adsorption of strontium from aqueous solutions onto PAN/zeolite composite. The strontium adsorption on the composite adsorbent was studied as a function of initial strontium concentration, pH of the solution, contact time and temperature. Adsorption isotherms like Langmuir, Freundlich, Dubinin-Radushkevich (D-R) and Temkin were used to analyze the equilibrium data at the d...

Fully modern human form more gracile than the antecedent archaic modern form was evident by 30,000 years ago. One hypothesis to explain this decrease in skeletal robustness is that change occurred in human diet and that this change was associated with a decrease in activity levels required in both individual and group behavior. It is possible to study dietary change directly using trace element...

As models of the composition and heterogeneous chemical reactions of the troposphere undergo refinement, novel application of state-of-the-art analytical techniques will be necessary to propound realistic characterizations of mineral dust chemistry. In this study, strontium carbonate particles treated with gaseous nitric acid and nitrogen dioxide were examined with X-ray absorption fine structu...

A many-body potential for strontium clusters is developed with parameters fitted to the energy surface of strontium clusters containing up to ten atoms calculated within the density functional theory in the generalized gradient approximation. Structure and energetics of the most stable cluster isomers with up to 63 atoms are obtained with genetic algorithms. Additionally, the high resolution ma...

Osteoarthritis is a primary cause of disability and functional incapacity. Pharmacological treatment is currently limited to symptomatic management, and in advanced stages, surgery remains the only solution. The therapeutic armamentarium for osteoarthritis remains poor in treatments with an effect on joint structure, that is, disease-modifying osteoarthritis drugs (DMOADs). Glucosamine sulfate ...

Strontium concentration and isotopic data for subsurface flowing groundwaters of the Ganges-Brahmaputra (G-B) delta in the Bengal Basin demonstrate that this is a potentially significant source of strontium to the oceans, equal in magnitude to the dissolved strontium concentration carried to the oceans by the G-B river waters. The strontium concentrations of groundwaters are higher by a factor ...

Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologie...