A retrospective review of the multicenter IPSYS CeAD (Italian project on stroke in young adults cervical artery dissection) study was performed from January 2000 to June 2019. Of 1283 patients with spontaneous dissection, mean age 48 years, 545 were women (43%), and 103 (8%) had a diagnosis coexistent cerebrovascular fibromuscular dysplasia (FMD). More FMD women. history migraine intracranial a...

We report a case study of mitochondrial encephalopathy, lac-tic acidosis, and stroke-like episode (MELAS) syndrome with presentation of headache and prolonged visual aura. Mitochondrial encephalopathy, lactic acidosis, and stroke-like episode syndrome is one of the most commonly recognized mitochondrial diseases. It is characterized by lactic aci-dosis, the occurrence of stroke-like episodes, a...

Migraine is one of the most common neurological disorders, affecting women disproportionally at a rate of 3:1. Prior to puberty, boys and girls are equally affected, but the female preponderance emerges after puberty. Migraine pathophysiology is not fully understood, and although the hormonal effect of estrogen is significant, other factors are at play. This article will focus on the hormonal i...

Migraine headaches affect approximately 13% of US population, affecting women in a 3:1 ratio and with a 60–80% familial inheritance. Migraine is a relevant social health problem; in fact it significantly restricts the social life of those who are affected. Recently, migraine headache has been suspected to be a potential risk factor for stroke, particularly in women, smokers and for those making...

OBJECTIVES Migraine is a risk factor for stroke in young women. Biomarker studies implicate endothelial activation as a possible mechanism. Emerging relationships of childhood adversity with migraine, and with inflammation, a component of endothelial activation, suggest that it may play a role in the migraine-stroke association. Our objective is to evaluate the relationship between adverse chil...

BACKGROUND AND PURPOSE In the general population, migraine, cerebrovascular diseases, and vascular dementia differ in many aspects between men and women. CADASIL is considered a unique model to investigate migraine with aura, stroke, and dementia related to ischemic small vessel disease. This study aims to evaluate the effect of gender on the main clinical and neuroimaging characteristics of CA...

background: the aim of this study was to evaluate whether higher serum levels of insulin-like growth factor-i (igf-i) in the acute phase of ischemic stroke are associated with less severe strokes and better functional outcome in a period of 12-month follow-up. methods: from october 2014 to august 2015, patients with the diagnosis of acute ischemic stroke admitted to the stroke unit of firoozgar...

= Abstract =MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episode) is a rare and currently incompletely defined mitochondrial disease involving mainly muscle and brain. We have recently seen a 17-year-old male patient who, we believe, is the first Korean case. The patient showed the classical picture of MELAS: short stature, generalized limb weakness, ...

Background Intravenous infusion of adenylate cyclase-activating polypeptide-38 (PACAP38) provokes migraine-like attacks in 65-70% of migraine sufferers. Whether aggregation of migraine in first-degree relatives contributes to this discrepancy in PACAP38-induced response is unknown. We hypothesized that genetic enrichment plays a role in triggering of migraine and that migraine without aura pati...

Regional cerebral blood flow (rCBF) asymmetries were studied in controls and patients with common and classic/complicated migraine using Xe inhalation with 8 homologously situated external collimators over each cerebral hemisphere. Migraine patients as a group more frequently had posterior rCBF asymmetries than controls (p<0.03). Although there were no differences in the number of anterior rCBF...