Mind-body interventions are beneficial in stress-related mental and physical disorders. Current research is finding associations between emotional disorders and vagal tone as indicated by heart rate variability. A neurophysiologic model of yogic breathing proposes to integrate research on yoga with polyvagal theory, vagal stimulation, hyperventilation, and clinical observations. Yogic breathing...

The major findings regarding the genetics of stress response and stress-related disorders are: (i) variations in genes involved in the sympathetic system or in the hypothalamic-pituitary-adrenocortical axis are associated with altered stress responses; (ii) genes related to the renin-angiotensin-aldosterone system or inflammation/immune response show associations with cardiovascular disorders; ...

Biochemical integrity of the brain is vital for normal functioning of the central nervous system (CNS). One of the factors contributing to cerebral biochemical impairment is a chemical process called oxidative stress. Oxidative stress occurs upon excessive free radical production resulting from an insufficiency of the counteracting antioxidant response system. The brain, with its high oxygen co...

Elevated levels of stress and anxiety often accompany vestibular dysfunction, while conversely complaints of dizziness and loss of balance are common in patients with panic and other anxiety disorders. The interactions between stress and vestibular function have been investigated both in animal models and in clinical studies. Evidence from animal studies indicates that vestibular symptoms are e...

This article is part of a Special Issue "SBN 2014". Stress is a potential etiology contributor to both post-traumatic stress disorders (PTSD) and major depression. One stress-related neuropeptide that is hypersecreted in these disorders is corticotropin releasing factor (CRF). Dysregulation of CRF has long been linked to the emotion and mood symptoms that characterize PTSD and depression. Howev...

STUDY OBJECTIVE To determine whether there is a relationship between musculoskeletal disorders and presumed symptoms of stress. DESIGN Cross sectional and mixed longitudinal cohort study. Longitudinal data were collected at baseline (1973) and at re-examinations in 1978 and 1983. SETTING Community based. PARTICIPANTS Study sample was drawn from employees who had worked for at least 15 mon...

OBJECTIVES To determine the prevalence of symptoms of depression, anxiety and stress among secondary school girls. METHODS A cross- sectional study was carried out on secondary school girls in Abha city, Aseer Region, Saudi Arabia, using the Arabic version of the Depression, Anxiety, and Stress Scale (DASS-42). RESULTS Of 545 female students recruited in this study, 73.4% had the symptoms o...

Anxiety disorders can lead to uneasiness, apprehension and ultimately become manifest with compulsions and panic attacks. These disturbances may even be a component of other behavior or psychiatric disorders such as depression, mania or psychosis. The biological basis of emotional disorders are broad and can be the result of multiple components that involve cellular pathways as well as environm...

The Research Domain Criteria (RDoC) initiative provides a strategy for classifying psychopathology based on behavioral dimensions and neurobiological measures. Neurodevelopment is an orthogonal dimension in the current RDoC framework; however, it has not yet been fully incorporated into the RDoC approach. A combination of both a neurodevelopmental and RDoC approach offers a multidimensional per...