Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening conditions associated with significant morbidity and mortality. They are considered to be part of a spectrum of cutaneous drug reactions, differing only by their extent of skin detachment due to keratinocyte apoptosis. Drugs are assumed as the main cause of Stevens-Johnson syndrome and toxic epidermal necrolysis in mos...

Due to fever, lymphadenopathy and rash, this condition has to be differentiated from viral infections especially infectious mononucleosis and also bacterial infections. Awareness of this entity helps in an early diagnosis. Treatment consists of omitting the offending drug and systemic steroids, if necessary. Our patient was managed symptomatically. REFERENCES 1. Mittal RR, Jain C, Walia RLS, Ch...

The Stevens-Johnson syndrome has the appearance of a partial-thickness burn that may lead to a 100% loss of epidermis, requiring the same resuscitation as a severe burn. A 38-yr-old male patient was admitted to the neurosurgery department of the Evangelismos General Hospital in Athens, where immediately after administration of an antiepileptic drug he developed sloughing of total epidermis, hig...

The Stevens-Johnson Syndrome, otherwise known as erythema multiforme exudativum, has lately become more widely recognised as being liable to present as an acute medical emergency. The case described here is of special interest for several reasons: it would seem to be the most severe example of the disease ever recorded, which did not end fatally; it was complicated by acute dysphagia necessitat...

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Stevens-Johnson syndrome is a rare but serious medical condition, which classified within the blistering diseases of skin and mucous membranes. It characterized by severe generalized immune-mediated inflammatory reaction, predominantly affecting membranes, such as eyes, mouth genitalia.

Fuchs' syndrome (Stevens-Johnson syndrome without skin involvement) is a sporadically diagnosed disease. Most authors consider it to be a pure mucosal variant of Stevens-Johnson syndrome; however, some consider the syndrome a separate entity. The complete absence of cutaneous symptoms may be the reason that not all cases of Fuchs' syndrome are diagnosed and properly classified. The authors desc...