HS: hidradenitis suppurativa IL: interleukin LCV: leukocytoclastic vasculitis PAPA: pyogenic arthritis, pyoderma gangrenosum, and acne PAPASH: pyogenic arthritis, pyoderma gangrenosum, acne, and hidradenitis suppurativa PASH: pyoderma gangrenosum, acne, and hidradenitis suppurativa PG: pyoderma gangrenosum PsAPASH: psoriatic arthritis, pyoderma gangrenosum, acne, and hidradenitis INTRODUCTION A...

BACKGROUND The incidence of preadolescent acne among women is increasing. Acne deteriorates the quality of life; conventional treatment options are limited and have not been effective against acne, particularly acne associated with menstruation. Despite evidence that acne associated with menstruation abnormalities naturally improves when menstruation recovers to normal, there have only been few...

INTRODUCTION The negative impact of acne on aspects of health-related quality of life (HRQL) has been demonstrated in many quantitative studies; however, there has been relatively little qualitative research exploring the impact of acne and the use of topical treatment. The study aimed to explore the impact of moderate-severe acne on HRQL in adolescents and adults with inflammatory and non-infl...

BACKGROUND Androgens are involved in the development of acne. The aim of this study was to find out if there was an association of serum testosterone and sex hormone binding globulin (SHBG) in females with acne based on its severity. METHODS It was a cross sectional study, conducted in Dermatology unit of Fauji Foundation Hospital (FFH), Rawalpindi. Duration of study was eight months. Adult f...

Novan Therapeutics | 4222 Emperor Boulevard, Suite 470, Durham, North Carolina 27703 | (919) 485-8080 | www.novantherapeutics.com Introduction Novan Therapeutics, a clinical-stage drugdevelopment company, has developed drug candidate SB204, which releases nitric oxide when applied topically to the skin. Based on results from animal studies, locally available nitric oxide may inhibit skin steroi...

Acne vulgaris is a common skin disorder and the available drugs have been shown to be associated with specific limitations. The present study was planned to evaluate the efficacy and safety of “Acne-N-Pimple Cream” in the management of acne vulgaris. This study was a prospective, open, non-comparative, phase III clinical trial and a total of 26 patients, who were diagnosed as suffering from acn...

UNLABELLED Acne surgery is the use of various surgical procedures for the treatment of postacne scarring and also, as adjuvant treatment for active acne. Surgery is indicated both in active acne and post-acne scars. PHYSICIANS' QUALIFICATIONS: Any Dermatologist can perform most acne surgery techniques as these are usually taught during postgraduation. However, certain techniques such as dermabr...

Circulating sex hormones follow major fluctuations during the ovarian cycle. The so-called premenstrual syndrome represents a global condition grouping the diversity of catamenial disorders. At the skin level, the sebaceous gland activity is obviously modulated by these endocrine fluctuations. In addition, a series of pathological manifestations take place simultaneously in some women. Among th...

BACKGROUND The use of oral flutamide is rarely investigated in acne therapy. The aim of this study was to compare the efficacy of oral flutamide with that of a cyproterone-estradiol combination in treating acne lesions. METHODS A randomized clinical trial enrolled patients with moderate acne into two equal groups to receive either oral flutamide or the cyproterone-estradiol combination for 6 ...