BACKGROUND AND PURPOSE Thrombolysis in acute stroke is effective up to 4.5 hours after symptom onset but relies on early recognition, prompt arrival in hospital, and timely brain scanning. This study aimed to establish the cost-effectiveness of increasing thrombolysis rates through a series of hypothetical change strategies designed to optimize the acute care pathway for stroke. METHODS A dec...

Amniotic fluid phospholipids from 346 patients' specimens were quantified and evaluated against the clinical outcome (i.e., respiratory distress syndrome or normal respiratory function). Concentrations of lecithin, sphingomyelin, phosphatidylglycerol, and the lecithin/sphingomyelin reflectance ratio were evaluated by ordered frequency distribution and stepwise discriminant function analysis. Th...

This paper presents two polynomial time algorithms for the constant capacitated lot sizing problem with a batch production. We give several optimality properties for the general problem. Assuming constant production capacity, constant batch size and WagnerWhitin cost structure, we derive O(T ) and O(T ) time algorithms respectively for the case with production capacity multiple of the batch siz...