Staphylococcal cassette chromosome mec (SCCmec) typing is essential for understanding the molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA). SCCmec elements are currently classified into types I to V based on the nature of the mec and ccr gene complexes, and are further classified into subtypes according to their junkyard region DNA segments. Previously described trad...

conclusions our results show the presence of clonal groups of enterotoxin-producing mrsa strains in this hospital in tehran. the presence of bacteriophage encoded virulence factors and resistance to oxacillin enable bacteria to produce a broad spectrum range of diseases. results out of the 279 s. aureus isolates, 91 (32.6%) strains were confirmed as mrsa. totally, 6 enterotoxin and 2 virulence ...

Background The remarkable ability of Staphylococcus aureus to acquire mobile genetic elements that carry virulence and antibiotic resistance genes, contributes to its success, pathogenicity and evolution. There is indirect evidence that methicillinresistant S. aureus (MRSA) clones arose from genetic transfer of staphylococcal cassette chromosome mec (SCCmec) from Staphylococcus epidermidis and ...

Molecular typing is an important tool in the investigation of methicillin resistant Staphylococcus aureus (MRSA) outbreaks and in following the evolution of MRSA. The staphylococcal cassette chromosome mec (SCCmec) contains a hypervariable region with a variable number of 40 bp repeats named direct repeat units (dru). The dru region has been suggested as a supplementary typing method for MRSA a...

Staphylococcus aureus is an ubiquitous bacterium that is frequently part of the human microflora, causing disease when the immune system becomes compromized. Although S. aureus can be found in different parts of the body, anterior nares are the main ecological reservoir in humans [1]. This versatile pathogen is responsible for a wide variety of diseases, including superficial, systemic and life...

Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has rarely been reported in the hospital setting. We report an outbreak of 7 cases of skin and soft tissue infections due to a strain of CA-MRSA. All patients were admitted to the labor and delivery, nursery, or maternity units during a 3-week period. Genetic fingerprinting showed that the outbreak strain was closely rel...

Staphylococcus aureus is a versatile Gram-positive coccus frequently found colonizing the skin and nasal membranes of humans. The acquisition of the staphylococcal cassette chromosome mec was a major milestone in the evolutionary path of methicillin-resistant S. aureus. This genetic element carries the mecA gene, the main determinant of methicillin resistance. MRSA is involved in a plethora of ...