OBJECTIVE The use of performance enhancing substances is banned in sports by the World Anti-Doping Agency (WADA). Though most prohibited substances can be detected by GC/MS, inclusion of corticosteroids and designer drugs has made it essential to detect these critical doping agents on LC/MS/MS due to their better separation and detection. MATERIALS AND METHODS A common extraction procedure fo...

by Kimberly T. Tsutsui, M.S. Washington State University May 2010 Chair: Rebecca. M. Craft Use of anabolic-androgenic steroids (AAS) has been anecdotally associated with pain reduction as well as opioid abuse. The purpose of the current study was to investigate the effects of AAS on nociception and morphine antinociception in acute pain models, as well as on chronic nociception in an arthritis ...

Objectives: The aim of this study was to identify active ingredients present in counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders. Preparations in closed or sealed packaging with different batch numbers (n = 74) and two preparations without labels were analyzed. Methods: The identification scheme was based on reversed-phase liquid chromatography w...

According to the regulations of the World Anti-Doping Agency (WADA) [1], anabolic androgenic steroids are classified as prohibited substances in sports. They are covered in the section “S1. Anabolic Agents 1. Anabolic Androgenic Steroids (AAS)”. This section is further subdivided into “a. Exogenous AAS” and “b. Endogenous AAS”. AAS represent the class of substances most frequently detected in h...