OBJECTIVE To understand general practitioners' (GPs) use of individual risk factors (blood pressure and cholesterol levels) versus absolute risk in cardiovascular disease (CVD) risk management decision-making. DESIGN Randomised experiment. Absolute risk, systolic blood pressure (SBP), cholesterol ratio (total cholesterol/high-density lipoprotein (TC/HDL)) and age were systematically varied in...

has been done of late years on the chemistry of pathological processes. The subject of Chemical Pathology is in its infancy, but it is fairly certain that the future of Pathology and even of Medicine will be closely bound up in it. Hitherto Pathology has been concerned chiefly with morphological questions, and rightly so, for the morphological problems are much easier to solve than the chemical...

BACKGROUND Inequalities in progress towards achievement of Millennium Development Goal four (MDG-4) reflect unequal access to child health services. OBJECTIVE To examine the time trends, socio-economic and regional inequalities of under-five mortality rate (U5MR) in Nepal. METHODS We analyzed the data from complete birth histories of four Nepal Demographic and Health Surveys (NDHS) done in ...

A data-driven block thresholding procedure for wavelet regression is proposed and its theoretical and numerical properties are investigated. The procedure empirically chooses the block size and threshold level at each resolution level by minimizing Stein’s unbiased risk estimate. The estimator is sharp adaptive over a class of Besov bodies and achieves simultaneously within a small constant fac...

We provide an estimate, sharp up to poly-logarithmic factors, of the asymptotically almost sure mixing time of the graph created by long-range percolation on the cycle of length N (Z/NZ). While it is known that the almost sure diameter drops from linear to poly-logarithmic as the exponent s decreases below 2 [4, 9], the almost sure mixing time drops from N only to N (up to poly-logarithmic fact...

A software usage models describes the prospective use of a program in its intended environment and allows the generation of random test cases leading to unbiased estimates of the failure risk, i.e., the expected loss by program failure. We concentrate on usage models of Markov type and show that by suitable changes of the probabilities of state transitions during test, the precision of the risk...

in this paper we compared multivariate garch models toestimate value-at-risk. we used a portfolio of weekly indexesincluding tedpix, klse, xu100 during ten years. to estimatevalue-at-risk, first we estimated ccc, dcc of engle, dcc of tseand tsui, dynamic equi correlation models by oxmetrics. then,optimum lags were estimated by minimizing the information criteria.to estimate var, the models accu...

“I am fairly sure of this that none ever willingly errs".

We study the properties of foreign exchange risk premia that can explain the forward bias puzzle – the tendency of high-interest rate currencies to appreciate rather than depreciate. These risk premia arise endogenously from the no-arbitrage condition we impose on the relation between the term structure of interest rates and exchange rates, and they compensate for both currency risk and interes...