an oral sustained-release floating tablet formulation of metformin hcl was designed and developed. effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and hpmc-peo polymer combination, respectively. tablet composition was optimized by response surface methodology (rsm). seventeen (17) trial formulations were analyzed according to box-behnken desi...

the paper is concerned with robust stability criteria for takagi- sugeno (t-s) fuzzy systems with distributed delays and time delay in the leakage term. by exploiting a model transformation, the system is converted to one of the neutral delay system. global robust stability result is proposed by a new lyapunov-krasovskii functional which takes into account the range of delay and by making use o...