In collagen, strands of the sequence XaaYaaGly form a triple-helical structure. The Yaa residue is often (2S,4R)-4-hydroxyproline (Hyp). The inductive effect of the hydroxyl group of Hyp residues greatly increases collagen stability. Here, electron withdrawal by the hydroxyl group in Hyp and its 4S diastereomer (hyp) is increased by the addition of an acetyl group or trifluoroacetyl group. The ...

Simona Botti is Assistant Professor of Marketing, S.C. Johnson Graduate School of Management, Cornell University (e-mail: sb376@ cornell.edu). Sheena S. Iyengar is Associate Professor of Management, Graduate School of Business, Columbia University (e-mail: [email protected]). The authors thank John Lynch, Alex Chernev, Kristin Diehl, and Anu Mitra for their careful, insightful review of a prev...

A procedure for the cyclization of dipeptidoyl benzotriazolides containing proline derivatives promoted by triethylamine under MW activation is introduced. The reaction is general for a variety of dipeptidoyl benzotriazolides and represents a very practical and convenient method for the preparation of Pro- or Hyp-derived 2,5-diketopiperazines (2,5-DKPs) and bis-DKPs with a disulfide linker. Thi...

Exotic plants often face different conditions from those experienced where they are native. The general issue of how exotics respond to unfamiliar environments within their new range is not well understood. Phenotypic plasticity has historically been seen as the primary mechanism enabling exotics to colonize large, environmentally diverse areas. However, new work indicates that exotics can evol...

We present preliminary results of B K calculated using improved staggered fermions with the mixed action (valence quarks = HYP staggered fermions and sea quarks = AsqTad staggered fermions). We analyze the data based upon the prediction by Van de Water and Sharpe. A hint of consistency with the prediction is observed. We also present preliminary results of B (3/2) 8 and B (3/2) 7. international...

The use of botanical dietary supplements has grown steadily over the last 20 years despite incomplete information regarding active constituents, mechanisms of action, efficacy, and safety. An important but underinvestigated safety concern is the potential for popular botanical dietary supplements to interfere with the absorption, transport, and/or metabolism of pharmaceutical agents. Clinical t...

We calculate one-loop matching factors for bilinear operators composed of improved staggered fermions. We compare the results for different improvement schemes used in the recent literature, including the HYP action and an action close to the Asqtad action. We find that all improvement schemes substantially reduce the size of the one-loop contributions to matching factors. The resulting correct...

t Michie, Nilsson, Gaschnig, etc. See, for example, Gaschnig 771 and the references he cites.). The second use, plausible move generation, is the source of power exploited by AM [Lenat 791. Tt has the character of lean? irlg by disco WY)). h the third and final case, the entities being learned are not new domain concepts, but new heuristics. Hypothesis 3: Heuristics can act as “plausible move g...

One of the top-selling medicinal products worldwide is Hypericum perforatum (St. John's Wort). Despite its cosmopolitan distribution and utilization, little is known regarding the relationship of the bioactive compounds in H. perforatum to the plants from which they are purportedly derived. In this study, amplified fragment length polymorphism (AFLP) analysis of 56 Hypericum accessions, represe...

T heologian John Shea, STD, writing several years ago about CHA's Mission-Centered Leadership Competency Model, said that in health ministry the first step from faith to practicality—that is, concrete action on behalf of mission—is values. "Faith convictions and narratives are expressed in the full-blown religious language of the Catholic tradition, for example, God, Christ, sin, redemption, ch...