www.aana.com/aanajournalonline.aspx Dexmedetomidine and ketamine infusions were the main anesthetic for a 15-year-old girl, who underwent scoliosis repair surgery with intraoperative wake-up test, somatosensory evoked potential (SSEP), and motorevoked potential (MEP) monitoring. To achieve maintenance of anesthesia, dexmedetomidine and ketamine were administered concomitantly. The dexmedetomidi...

In progressive myoclonic epilepsy (PME), a rare epileptic syndrome caused by a variety of genetic disorders, the combination of peripheral stimulation and functional magnetic resonance imaging (fMRI) can shed light on the mechanisms underlying cortical dysfunction. The aim of the study is to investigate sensorimotor network modifications in PME by assessing the relationship between neurophysiol...

OBJECTIVE To investigate the association between baseline motor evoked potential (MEP) and somatosensory evoked potential (SSEP) responses in the lower extremities and balance recovery in subacute hemiparetic stroke patients. METHODS MEPs and SSEPs were evaluated in 20 subacute hemiparetic stroke patients before rehabilitation. Balance (static posturography and Berg Balance Scale [BBS]), moto...

Various intraoperative neurophysiological monitoring (IONM) helps in assessing the integritry of neural pathways during surgical treatment. IONM is an assistive tool to preserve fuction brain, brainstem, cranial nerve, spinal cord and peripheral nerves a great assest for neurosurgeons. Different application includes: MEP, SSEP, ABR, VEP, BCR AMR. Intraoperative neuromonitoring has become integr...

Burst-mode focused ultrasound (FUS) induces microbubble cavitation in the vasculature and temporarily disrupts the blood-brain barrier (BBB) to enable therapeutic agent delivery. However, it remains unclear whether FUS-induced BBB opening is accompanied by neuromodulation. Here we characterized the functional effects of FUS-induced BBB opening by measuring changes in somatosensory evoked potent...

Neural oscillations are the intrinsic characteristics of brain activities. Traditional electrophysiological techniques (e.g., the steady-state evoked potential, SSEP) have provided important insights into the mechanisms of neural oscillations in the high frequency ranges (>1 Hz). However, the neural oscillations within the low frequency ranges (<1 Hz) and deep brain areas are rarely examined. B...

An acute subdural hematoma (ASDH) induces pathomechanisms which worsen outcome after traumatic brain injury, even after a small hemorrhage. Synergistic effects of a small ASDH on brain damage are poorly understood, and were studied here using neuromonitoring for 10 h in an injury model of controlled cortical impact (CCI) and ASDH. Pigs (n = 32) were assigned to 4 groups: sham, CCI (2.5 m/s), AS...

OBJECTIVE To share our experience of anaesthetic management of scoliosis with intra-operative somatosensory evoked potential monitoring and wake up test. METHODS All the cases of scoliosis surgery scheduled during a period of two years in which SSEP and intra-operative wake-up test was planned were included in the study. The patient in which intra-operative wake-up test was not planned were e...

We report on our experience with long-term monitoring of the EEG power spectrum and somatosensory evoked potentials (SSEPs) in 103 patients with severe closed head injury (Glasgow Coma Scale-GCS < or = 8). Patients were monitored for an average of 5 days post injury and monitoring was terminated when they died, regained consciousness or their intracranial physiologic parameters (primarily intra...