Using the measure of Physiologically Equivalent Temperature (PET) it is analysed how changes in the thermal environment can affect human well-being. Historical data used in this study have been assembled for the normal climate period 1961–1990 (CNTRL). Future conditions are calculated based on the period 2071–2100, for which simulated datasets are available, based on GCMs integrated with scenar...

Effective conservation and utilization strategies for natural biological resources require a clear understanding of the geographic distribution of the target species. Tricholoma matsutake is an ectomycorrhizal (ECM) mushroom with high ecological and economic value. In this study, the potential geographic distribution of T. matsutake under current conditions in China was simulated using MaxEnt s...

This article assesses the effect of potential future climate change on streamflow in the Luohe River basin. The predicted future climate change by two SRES (Special Report on Emissions Scenarios) climate change scenarios (A2 and B2) and two general circulation models (HadCM3 and CGCM2) were applied. SWAT (Soil and Water Assessment Tool), a physically based distributed hydrological model, was ca...

This chapter reviews three scenario literatures: general mitiga-tion scenarios produced since the Second Assessment Report (SAR), narrative-based scenarios found in the general futures literature, and mitigation scenarios based on the new reference scenarios developed in the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES). Scenarios A long-term view...

Acquiring high-quality rainfall data is very important for studying catchment hydrology. This can be obtained by merging Satellite Rainfall Estimates (SREs) and gauge observations as highlighted several researchers. However, the application of these merged products hydrological modeling has rarely been explored in a complex topographic region like Melkakuntire catchment, Ethiopia. Therefore, th...

Comparisons of models with observations for sulfate aerosols and other sulfur compounds are particularly relevant for assessing model capabilities because the emissions of sulfur bearing compounds are better known than the emissions of other aerosol compounds. Thus, comparison can focus on the capabilities of the models to treat transport and oxidation processes. Recent field studies, however, ...

Abstract. Climate policy analysis needs reference scenarios to assess emission targets and current trends. When presenting their national climate policies, countries often showcase target trajectories against fictitious so-called baselines. These counterfactual are meant present future greenhouse gas (GHG) emissions in the absence of policy. baselines presented by limited use, as they can be ex...

BACKGROUND Bone metastases are a common complication of prostate cancer, so treatment and prevention are essential to slow the progression of the disease and the occurrence of skeletal related events (SREs), which have devastating consequences for the quality of life of patients. SUMMARY OF EVIDENCE Bone metastases are characterized by increased bone turnover and altered balance between osteo...

In a placebo-controlled randomized clinical trial, zoledronic acid (4 mg via a 15-minute infusion every 3 weeks for 15 months) reduced the incidence of skeletal-related events (SREs) in men with hormone-refractory metastatic prostate cancer. Among 122 patients who completed a total of 24 months on study, fewer patients in the 4-mg zoledronic acid group than in the placebo group had at least one...

Synonymous gene regulation, defined by regulatory elements driving shared temporal and/or spatial aspects of gene expression, is most probably predicated on genomic elements that contain similar modules of certain transcription factor binding sites (TFBS). We have developed a method to scan vertebrate genomes for evolutionary conserved modules of TFBS in a predefined configuration, and created ...