the aim of this study was to ascertain the prevalence of human papillomavirus (hpv) 16/18 in oral squamous cell carcinoma (oscc) and normal oral mucosa in iranian individuals with oscc and their association with various risk factors. the investigation followed a hospital-based case-control design. cases were individuals with diagnosed oscc, age- and sex-matched with controls. sixty-six paraffin...

background & objective: chronic non healing ulcers or scar undergoing malignant transformation is a rare phenomenon with an estimated incidence of 2%. though, numerous predisposing factors have been identified, still it is rarely diagnosed and commonly mistaken for a benign condition. the objective of this study was to verify the efficacy of the fine needle aspiration cytology/ scrape cytol...

background: esophageal cancer is the sixth cause of death in the world, there was a lack of population‑based information on the trend and incidence rate of esophagus cancer, so this study aimed to determine the incidence and pathological changes of esophagus cancer in iran. methods: in this study, data were extracted from annual cancer registry reports of iranian ministry of health between 2003...

Background: Non melanoma skin cancer (NMSC) is the most common cancer worldwide. In most cases, the general outlook is excellent; however, local recurrence or metastasis can occur. In this study, we investigated possible tumor and host characteristics affecting the treatment outcome in our department of radiation oncology.Method: We retrospectively studied cases with non melanoma skin cancer (N...

BACKGROUND In the United States, approximately 2500 cases of cholangiocarcinoma occur each year. The average incidence is 1 case/100 000 persons each year. Surgical resection is the mainstay for the treatment of cholangiocarcinoma. The result of surgery depends on location of the tumor, extent of tumor penetration of the bile duct, tumor-free resection margins, and lymph node and distant metast...

introduction: esophageal squamous-cell carcinoma (scc) is one of the most common malignancies in iran. to reduce the incidence of esophageal scc, it is important to recognize the controllable risk factors and prevent them. celiac disease is widely known as a possible risk factor for esophageal scc.  thus, we decided to assess the frequency of celiac disease in esophageal scc patients in north e...

it has been argued that oral lichen planus (olp) may increase the risk of oral cancer. patients with olp may be at an increased risk for developing of oscc (oral squamous cell carcinoma). here, the author reports a case of olp initially presenting with a clearly benign olp lesion that transformed into oscc over a course of 18 months. this report may provide a clear evidence for olp lesion as a ...

esophageal squamous cell carcinoma is a rather common cancer in northern iran. incidence of adenocarcinoma of esophagus has an increasing trend in iran. co-existence of both cancers in one patient is very rare. we report a middle age woman from northern iran with a typical presentation of esophageal cancer, who was found to have a dual esophageal cancer. the disease was found in the advanced st...

esophageal cancer (ec) is the eighth most common cancer and sixth most frequent cause of cancer mortality worldwide. esophageal squamous cell carcinoma (escc) is the most common type of ec. escc develops by progression from premalignant lesions, which are called esophageal squamous dysplasia (esd). prevention is the most effective strategy for controlling this disease. generally, two methods ma...

snus (nass) is a form of snuff used in a similar manner to american dipping tobacco, but it does not typically result in a need for spitting. possible hazards associated with this material include malignant and premalignant lesions in the oral cavity and gastrointestinal tract. the use of smokeless tobacco has increased in the middle east in recent decades, particularly among teenagers and youn...